Cancer Biology & Genetics Program
The Scott Lowe Lab
Research

Professor
About the Scott Lowe Lab
Our laboratory studies tumor-suppressor networks controlling apoptosis and senescence and how their disruption influences malignant behavior.
Research Projects
Inside My Lab: Scott Lowe

Featured News



Publications
Burdziak C, Alonso-Curbelo D, Walle T, Reyes J, Barriga FM, Haviv D, Xie Y, Zhao Z, Zhao CJ, Chen HA, Chaudhary O, Masilionis I, Choo ZN, Gao V, Luan W, Wuest A, Ho YJ, Wei Y, Quail DF, Koche R, Mazutis L, Chaligné R, Nawy T, Lowe SW, Pe’er D.Science. 2023 May 12;380(6645):eadd5327. doi: 10.1126/science.add5327. Epub 2023 May 12.PMID: 37167403
Chen HA, Ho YJ, Mezzadra R, Adrover JM, Smolkin R, Zhu C, Woess K, Bernstein N, Schmitt G, Fong L, Luan W, Wuest A, Tian S, Li X, Broderick C, Hendrickson RC, Egeblad M, Chen Z, Alonso-Curbelo D, Lowe SW.Cancer Discov. 2023 Feb 6;13(2):432-453. doi: 10.1158/2159-8290.CD-22-0528.PMID: 36302222 Free PMC article.
People

Scott W. Lowe, PhD
Chair, Cancer Biology & Genetics Program, SKI; Chair, Geoffrey Beene Cancer Research Center; Investigator, Howard Hughes Medical Institute
Professor
- Cancer biologist Scott Lowe uses genetically engineered mouse models to study how the genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response, and create molecular vulnerabilities that may be targeted therapeutically.
- PhD, Massachusetts Institute of Technology
- [email protected]
- Email Address
- 646-888-3342
- Office Phone
- Download CV
- PDF File
Members

- PhD, Cancer Research UK Beatson Institute, University of Glasgow, Scotland, United Kingdom
- 646-888-3340
- Lab Phone

- BS, University of California, Santa Barbara, CA
- 646-888-3340
- Lab Phone

- PhD, Stanford University, Stanford, CA
- 646-888-3340
- Lab Phone

- PhD, Autonomous University of Madrid, Spain
- 646-888-3340
- Lab Phone

- MD, Johannes-Gutenberg-University, School of Medicine, Mainz, Germany
- 646-888-3340
- Lab Phone

- PhD, Cold Spring Harbor Laboratory, New York
- 646-888-3340
- Lab Phone

- BS, The College of New Jersey, Ewing, NJ
- 646-888-3340
- Lab Phone

- PhD, Imperial College London, United Kingdom
- 646-888-3340
- Lab Phone

- PhD, Netherlands Cancer Institute (Netherlands)
- 646-888-3340
- Lab Phone

- PhD, Harvard University, Cambridge, MA
- 646-888-3340
- Lab Phone

- PhD, Harvard University, Cambridge, MA
- 646-888-3340
- Lab Phone

- PhD, Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY
- 646-888-3340
- Lab Phone

- PhD, Columbia University, New York, NY
- 646-888-3340
- Lab Phone

- MD, Capital University of Medical Sciences (China)
- 646-888-3340
- Lab Phone

- MS, University of Turku (Finland)
- 646-888-3340
- Lab Phone


- MS, Stony Brook University


- PhD, University of Rennes 1
- 646-888-3340
- Lab Phone

- Stanford University
- 646-888-3342
- Office Phone

Postdoctoral Researcher

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Graduate Student

Postdoctoral Researcher

Computational Biologist

Graduate Student

Postdoctoral Researcher

Postdoctoral Researcher

Postdoctoral Researcher

Postdoctoral Researcher

Postdoctoral Researcher

Postdoctoral Researcher

Mouse Colony Manager

Lab Manager

Senior Research Technician

Senior Research Technician

Research Technician

Research Technician

Administrative Coordinator

Assistant to Chair

Lead Program Manager

Postdoctoral Researcher

- PhD, Centro Nacional de Investigaciones Oncológicas [CNIO] (Spain)

- PhD, Universitat Pompeu Fabra and Institute for Research in Biomedicine [IRB] Barcelona (Spain)

- MD, Westphalian Wilhelms University (Germany)

- MD, Universidad Complutense de Madrid (Spain)
- PhD, Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY

- PhD, Medical Research Council, Clinical Sciences Centre, Imperial College London (UK)

- PhD, University of Konstanz (Germany)

- PhD, Weill Cornell Medical College, New York, NY
- MD, National Taiwan University (Taiwan)

- BS, National Taiwan University (Taiwan)
- PhD, Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY

- PhD, University of Michigan, Ann Arbor, MI

- PhD, University of Melbourne (Australia)

- PhD, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, NY

- PhD, Weill Cornell Medical College, New York, NY

- PhD, Northwestern University Feinberg School of Medicine, Chicago, IL

- MS, The Ohio State University, Columbus, OH
- PhD, Weill Cornell Medical College, New York, NY

- PhD, Weill Cornell Medical College, New York, NY

- PhD, Gerstner Sloan Kettering Graduate School, New York, NY

- PhD, University of Heidelberg (Germany)

- MD, University of Tübingen (Germany)

- PhD, Albert Einstein College of Medicine, New York, NY

- PhD, The Rockefeller University, New York, NY

- PhD, Weill Cornell Medical College, New York, NY

- PhD, Gerstner Sloan Kettering Graduate School, New York, NY

- PhD, Massachusetts Institute of Technology, Cambridge, MA

- PhD, Weill Cornell Medical College, New York, NY

- PhD, Centro Nacional de Investigaciones Oncológicas [CNIO] (Spain)

- PhD, Centro Nacional de Investigaciones Oncológicas [CNIO] (Spain)

- PhD, Baylor College of Medicine, Houston, TX

- PhD, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, NY

- PhD, University of Frankfurt (Germany)

- PhD, University of California, San Francisco, CA

- MD-PhD, Weill Cornell Medical College, New York, NY

- PhD, The Scripps Research Institute, La Jolla, CA

- PhD, University of California, Los Angeles, CA

- MD, Hannover Medical School (Germany)

- MD, University of Leipzig (Germany)


- PhD, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, NY

- MD, RWTH Aachen (Germany)

- PhD, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, NY

- MD, Medical University of China (China)
- PhD, Stony Brook University, New York

- BS, Carnegie Mellon University, Pittsburgh, PA

- MS, New York University

- BS, University of Connecticut

- AALAS Technician Certification

- BS, Yale University

- BS, Molloy College

- BA, City College of New York

- MS, New York University
- BSE, University of Pennsylvania

- BS, Binghamton University

- BS, Stony Brook University

- BS, Fairleigh Dickinson University

- BA, Hunter College

- MSc Oxon, University of Oxford (England)

- BS, University of Cincinnati
Lab Alumni

Junior Group Leader, Cancer Science, IRB Barcelona, Spain

Group Leader - Cancer Genome Engineering Lab Vall D´Hebron Institute of Oncology (VHIO)

Physician, University Hospital RWTH Aachen, Germany

CSHL Independent Fellow at Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

Group Leader, German Cancer Research Center (DKFZ), Heidelberg, Germany

Principal Scientist, CTI, Pfizer Research, New York

Data Scientist, Agios Pharmaceuticals, Inc., Cambridge, MA

Postdoctoral Fellow at Rockefeller University, New York, NY

Professor, Sichuan University, Sichuan, China

Assistant Professor, Weill Cornell Medical College, New York, NY

Director, Medical & Scientific Strategy, BluPrint Oncology, London

Senior Scientist, Oncology Biomarker Development, Genentech, San Francisco, CA

Associate Director, Liver Research, Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY

Postdoctoral Fellow, Harvard University, Cambridge, MA

Co-Founder & CEO, Algen Biotechnologies, San Francisco, CA

Postdoctoral Associate, Weill Cornell Medicine, New York, NY

Senior Research Scientist, Philipps University of Marburg, Institute of Pharmacology, Germany

Group Leader, University of Tübingen, Germany

Professor, Sichuan University, Sichuan, China

Senior Research Analyst, Biotechnology and Pharmaceuticals, Chardan Capital Markets LLC, New York, NY

Group Leader, Altos Labs, San Francisco, CA

Analyst, Nexttech, Boston, MA

Assistant Professor of Biology, Massachusetts Institute of Technology, Cambridge, MA

Senior Research Associate, Intelligencia, New York, NY

Associate Professor, Mount Sinai School of Medicine, New York, NY

Senior Principal Scientist, Novartis, Basel, Switzerland

Assistant Director, DNALC, Cold Spring Harbor Laboratory, New York

Senior Scientist, Pfizer, San Francisco, CA

Group Leader and Medical Fellow, University Medical Center Freiburg, Germany

Assistant Professor, Department of Pharmacology, University of North Carolina, Chapel Hill, NC

Investments, Roivant Sciences, New York, NY

Clinical Fellow, Pediatrics, Boston Children's Hospital, Boston, MA

Assistant Professor, Molecular, Cell & Cancer Biology, University of Massachusetts Medical School, Worcester, MA

Physician, Hannover Medical School, Germany

Physician, Hannover Medical School, Germany

Chair, Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN

Senior Scientist, Functional Genomics, Target Sciences, Pfizer, New York, NY

Group Leader, German Cancer Research Center (DKFZ), Heidelberg, Germany

Strategic Partnering Associate, Roche, Basel, Switzerland

Pathology Resident, The Mount Sinai Hospital, New York, NY

Research Specialist, Weill Cornell Medicine, New York, NY

Research Technician

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Laboratory Manager
Lab News & Events
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Lab Resources
Scott Lowe Lab Plasmid and Animal Requests
Request plasmids through Addgene More »
For plasmids not listed on Addgene, please contact our Lab Manager, Anne Trumble-Koncelik, [email protected].
For animal requests, please contact our Mouse Colony Manager, Janelle Simon, [email protected].
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Scott W. Lowe discloses the following relationships and financial interests:
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Blueprint Medicines
Equity; Professional Services and Activities -
Eli Lilly and Company
Equity -
Faeth Therapeutics, Inc
Equity; Professional Services and Activities (Uncompensated) -
Fate Therapeutics
Intellectual Property Rights; Professional Services and Activities -
Geras Bio Inc
Equity; Professional Services and Activities (Uncompensated)
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Mirimus
Equity; Professional Services and Activities -
Oric Pharmaceuticals
Equity; Professional Services and Activities -
PMV Pharma
Equity; Professional Services and Activities -
Senescea Therapeutics
Equity; Intellectual Property Rights; Professional Services and Activities (Uncompensated)
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].