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Stella Paffenholz, PhD

Analyst, Nexttech, Boston, MA

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Stella Paffenholz, MS

Dissertation

Flexible Preclinical Models of High-Grade Serous Ovarian Carcinoma to Elucidate Mechanisms of Treatment Sensitivity and Resistance (2022)

Mentor

Scott W. Lowe, PhD

Start Year

2016

End Year

2022

Education

PhD, Gerstner Sloan Kettering Graduate School, New York, NY

Graduate Student in Lowe Lab from 2016-2022.

Publications

Paffenholz SV, Salvagno C, Ho YJ, Limjoco M, Baslan T, Tian S, Kulick A, de Stanchina E, Wilkinson JE, Barriga FM, Zamarin D, Cubillos-Ruiz JR, Leibold J, Lowe SW. (2022) Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer. Proc Natl Acad Sci USA.

Sánchez-Rivera FJ, Diaz BJ, Kastenhuber ER, Schmidt H, Katti A, Kennedy M, Tem V, Ho YJ, Leibold J, Paffenholz SV, Barriga FM, Chu K, Goswami S, Wuest AN, Simon JM, Tsanov KM, Chakravarty D, Zhang H, Leslie CS, Lowe SW, Dow LE. (2022) Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants. Nat Biotechnol. Online ahead of print.