Molecular Biology Program

The Xiaolan Zhao Lab

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Research

Pictured: Xiaolan Zhao
Xiaolan Zhao, PhD


Professor

Our lab studies two fundamental aspects of biology that have broad implications for human health. The first research direction examines how cells faithfully duplicate their genomes and repair DNA lesions arising from endogenous and exogenous sources. The second direction focuses on how a protein modifier called SUMO mediates signal transduction, directs the DNA stress response, and dynamically regulates the functions of many proteins. We have implemented a versatile combination of molecular, genetic, biochemical, cell biological, and genomic/proteomic approaches toward answering these questions. Our current work aims to elucidate new underlying principles of the above processes, and reveal how they are integrated with other cellular functions to achieve cell proliferation under various conditions.

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Xiaolan Zhao Lab

Publications

People

Pictured: Xiaolan Zhao

Xiaolan Zhao, PhD



Professor

  • Molecular biologist Xiaolan Zhao studies chromosomal organization, genome integrity, DNA replication and repair, dynamic protein modification.
  • PhD, Columbia University
zhaox1@mskcc.org
Email Address
212-639-5582
Office Phone

Members

Nalini Dhingra
Nalini Dhingra

Research Associate

Shibai Li, PhD
Shibai Li

Research Scholar

Xiangzhou  Meng
Xiangzhou Meng

Research Scholar

Gemma Regan-Mochrie
Gemma Regan-Mochrie

Graduate Student

Nicole Clerico
Nicole Clerico

Administrative Assistant II

Jiayi Fan
Jiayi Fan

Research Scholar

Danying Guan
Danying Guan

Undergraduate Researcher

Tammy Yang

Undergraduate Researcher

Lab Alumni
Yu-Huang (Jeffrey) Chen

Former Graduate Student

Koyi Choi

Former Graduate Student

Prabha Sarangi

Former Graduate Student

Lisa Hang

Former Graduate Student

Bingbing Wan
Bingbing Wan

Former Research Associate

Jaclyn Bonner
Jaclyn Bonner

Former Graduate Student

Xiao Peng
Xiao Peng

Former MD/PhD Student

Lei Wei
Lei Wei

Former Graduate Student

Catherine
Catherine Cremona

Former Postdoctoral Fellow

Inn Chung, PhD
Inn Chung

Former Research Fellow

Shelly Lim
Shelly Lim

Former Postdoctoral Fellow

Wei Tan
Wei Tan

Former Research Fellow

Milica
Milica Arneric

Former Postdoctoral Fellow

Vladimir Yong-Gonzalez
Vladimir Yong-Gonzalez

Former Postdoctoral Fellow

Xianpeng Liu

Former Postdoctoral Fellow

Sadia
Sadia Rahman

Former Technician

Yan
Yan Yang

Former Technician

Jacqueline Arenz
Jacqueline Arenz

Former Technician

Fanfan
Fanfan Hao

Former Research Assistant

Jeannette
Jeannette Huaman

Former Summer Research Intern

Yoona
Yoona Lee

Former Undergraduate Intern

Silva Baburyan
Silva Baburyan

Former Undergraduate Researcher

Dennis Lysov
Dennis Lysov

Former Undergraduate Researcher

Lab Affilations

Achievements

  • Bressler Scholar, Alfred W. Bressler Scholar Endowment Fund (2007-2010)
  • Research Scholar, American Cancer Society (2012-2016)
  • Scholar, Leukemia & Lymphoma Society (2013-2018)
  • Discovery of the extensive SUMO-based DNA damage response
  • Discovery of the connection between the nuclear pore complex and desumoylation
Read more
  • Discovery of the Smc5/6 complex in budding yeast
  • Discovery of the essential function of the DNA replication and damage checkpoint

Open Positions

Postdoctoral, Graduate Student, & Technician Positions

Positions are available for postdoctoral fellows, graduate students, and technicians in the research group of Dr.

Apply now

Get in Touch

Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Xiaolan Zhao discloses the following relationships and financial interests:

  • Gordon Research Conference
    Provision of Services

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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