Immunology Program

The Michael Glickman Lab

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Research

Michael Glickman
Michael S. Glickman, MD


Professor

We are broadly interested in the biology of mycobacteria, which include the major human pathogen M. tuberculosis, the nonpathogenic model organism M. smegmatis, and the cancer biotherapeutic agent BCG.

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Research Projects

Michael Glickman Lab

Featured News

Michael Glickman
At Work: Infectious Diseases Specialist Michael Glickman

MSK physician-scientists Michael Glickman and Gil Redelman-Sidi
The ABCs of BCG: Oldest Approved Immunotherapy Gets New Explanation

Pictured: Eric Pamer & Joao Xavier
Turning to Bacteria for Clues

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Publications

A multilayered repair system protects the mycobacterial chromosome from endogenous and antibiotic-induced oxidative damage. Dupuy P, Howlader M, Glickman MS. Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):19517-19527. doi: 10.1073/pnas.2006792117. Epub 2020 Jul 29. PMID: 32727901

Bacterial immunotherapy for cancer induces CD4-dependent tumor-specific immunity through tumor-intrinsic interferon-γ signaling. Antonelli AC, Binyamin A, Hohl TM, Glickman MS, Redelman-Sidi G. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18627-18637. doi: 10.1073/pnas.2004421117. Epub 2020 Jul 17. PMID: 32680964

Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease. Wipperman MF, Heaton BE, Nautiyal A, Adefisayo O, Evans H, Gupta R, van Ditmarsch D, Soni R, Hendrickson R, Johnson J, Krogan N, Glickman MS. Mol Cell. 2018 Oct 4;72(1):152-161.e7. doi: 10.1016/j.molcel.2018.07.037. Epub 2018 Aug 30. PMID: 30174294

Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria.Fay A, Czudnochowski N, Rock JM, Johnson JR, Krogan NJ, Rosenberg O, Glickman MS. mBio. 2019 Jun 25;10(3):e00850-19. doi: 10.1128/mBio.00850-19.

The Canonical Wnt Pathway Drives Macropinocytosis in Cancer. Redelman-Sidi G, Binyamin A, Gaeta I, Palm W, Thompson CB, Romesser PB, Lowe SW, Bagul M, Doench JG, Root DE, Glickman MS. Cancer Res. 2018 Aug 15;78(16):4658-4670. doi: 10.1158/0008-5472.CAN-17-3199. Epub 2018 Jun 5.

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People

Michael Glickman

Michael S. Glickman, MD



Professor

  • Physician-scientist Michael Glickman investigates the physiology and pathogenic mechanisms of mycobacteria, including regulated intramembrane proteolysis (the Rip1 pathway); double-strand-break repair and associated DNA damage responses; and cell envelope biosynthesis.
  • MD, Columbia University College of Physicians and Surgeons
glickmam@mskcc.org
Email Address
646-888-2368
Office Phone
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Physician profile

Members

Michael Glickman, MD
Michael Glickman

Member

John Buglino, PhD
John Buglino

Senior Research Scientist

Allison Fay, PhD
Allison Fay

Senior Research Scientist

Gil Redelman-Sidi, MD
Gil Redelman-Sidi

Assistant Attending Physician

Oyindamola Adefisayo, BA
Oyindamola Adefisayo

Graduate Student

Anthony Antonelli
Anthony Antonelli

Graduate Student

Jamie Bean
Jamie Bean

TBRU Data Coordinator

Anna Binyamin

Lab Manager

Pierre Dupuy
Pierre Dupuy

Research Fellow

Adam Krebs
Adam Krebs

Graduate Student

Gaurav Sankhe
Gaurav Sankhe

Research Scholar

Miroslav Skular
Miroslav Skular

Research Technician

Charles Vorkas, MD
Charles Vorkas

ID fellow

Lab Alumni
Hitesh Bhattarai
Hitesh Bhattarai

Graduate Student

Richa Gupta, PhD
Richa Gupta

Research Fellow

Kendra Harris
Kendra Harris

Graduate Student

Brook Heaton

Research Scholar

Nathaniel Lazar

Graduate Student

Shilpa Reddy
Shilpa Reddy

Research Technician

Jessica Schneider
Jessica Schneider

Graduate Student

Han-guang Yan
Han-guang Yan

Senior Research Technician

Olivier Levy, PhD
Olivier Levy

Postdoctoral Fellow

Bernadette Lynn

Technician

Ashta Nautiyal
Ashta Nautiyal
Dave van Ditmarsch, PhD
Dave van Ditmarsch

Research Associate

Matthew Wipperman, Ph.D., M.Sc
Matthew Wipperman

Postdoctoral Fellow

Nicolas Stephanou
Daniel Barkan

Fellow

Vivek Rao
Hideki Makinoshima
Feng Gao
Pratima Kunwar
Paola Bongiorno
Jideofer Aniukwu
Linda Chu
Christina Stallings
Hock-Yong E
Joseph Sklar, PhD
Joseph Sklar

Research Fellow

Lab Affiliations

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Michael S. Glickman discloses the following relationships and financial interests:

  • Takeda Millennium
    Provision of Services
  • Vedanta
    Ownership / Equity Interests; Provision of Services

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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