Michael S. Glickman: Publications

Michael S. Glickman: Publications

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A multilayered repair system protects the mycobacterial chromosome from endogenous and antibiotic-induced oxidative damage. Dupuy P, Howlader M, Glickman MS. Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):19517-19527. doi: 10.1073/pnas.2006792117. Epub 2020 Jul 29. PMID: 32727901

Bacterial immunotherapy for cancer induces CD4-dependent tumor-specific immunity through tumor-intrinsic interferon-γ signaling. Antonelli AC, Binyamin A, Hohl TM, Glickman MS, Redelman-Sidi G. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18627-18637. doi: 10.1073/pnas.2004421117. Epub 2020 Jul 17. PMID: 32680964

Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease. Wipperman MF, Heaton BE, Nautiyal A, Adefisayo O, Evans H, Gupta R, van Ditmarsch D, Soni R, Hendrickson R, Johnson J, Krogan N, Glickman MS. Mol Cell. 2018 Oct 4;72(1):152-161.e7. doi: 10.1016/j.molcel.2018.07.037. Epub 2018 Aug 30. PMID: 30174294

Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria.Fay A, Czudnochowski N, Rock JM, Johnson JR, Krogan NJ, Rosenberg O, Glickman MS. mBio. 2019 Jun 25;10(3):e00850-19. doi: 10.1128/mBio.00850-19.

The Canonical Wnt Pathway Drives Macropinocytosis in Cancer. Redelman-Sidi G, Binyamin A, Gaeta I, Palm W, Thompson CB, Romesser PB, Lowe SW, Bagul M, Doench JG, Root DE, Glickman MS. Cancer Res. 2018 Aug 15;78(16):4658-4670. doi: 10.1158/0008-5472.CAN-17-3199. Epub 2018 Jun 5.

Redelman-Sidi, G., Iyer, G., Solit, D., and Glickman, M.S. Oncogenic activation of Pak1 dependent Macropinocytosis pathway determines BCG entry into bladder cancer cells. Cancer Res. 2013 Feb 1;73(3):1156-67.

Gupta R, Unciuleac MC, Shuman S, Glickman MS. Homologous recombination mediated by the mycobacterial AdnAB helicase without end resection by the AdnAB nucleases. Nucleic Acids Res. 2017 Jan 25;45(2):762-774. doi: 10.1093/nar/gkw1130. Epub 2016 Nov 29.

Wipperman MF, Fitzgerald DW, Juste MAJ, Taur Y, Namasivayam S, Sher A, Bean JM, Bucci V, Glickman MS. Antibiotic treatment for Tuberculosis induces a profound dysbiosis of the microbiome that persists long after therapy is completed.Sci Rep. 2017 Sep 7;7(1):10767. doi: 10.1038/s41598-017-10346-6.

Lazar N, Fay A, Nandakumar M, Boyle KE, Xavier J, Rhee K, Glickman MS. Control of biotin biosynthesis in mycobacteria by a pyruvate carboxylase dependent metabolic signal. Mol Microbiol. 2017 Dec;106(6):1018-1031. doi: 10.1111/mmi.13865. Epub 2017 Nov 17.