Cancer Biology & Genetics Program
The Joan Massagué Lab
Research
Professor
We are interested in metastasis, the cause of 90% of cancer deaths. The lab investigates metastatic stem cells and their stromal niches. The role of immune regulatory and regenerative signals, particularly TGF-β, is of interest. General as well as organ-specific mediators of metastasis are under investigation. We are defining the phenotypic plasticity and evolution of metastatic cell populations from dormancy to outbreak, identifying drug targets, and enabling clinical trials to treat metastasis.
Inside My Lab: Joan Massagué
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People
Joan Massagué, PhD
Member, Cancer Biology & Genetics Program; Marie-Josée and Henry Kravis Foundation Chair; Director, Sloan Kettering Institute
Professor
- Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.
- PhD, University of Barcelona
- j-massague@ski.mskcc.org
- Email Address
- 646-888-2044
- Office Phone
Members
Research Associate
Senior Research Assistant
Research Associate
Graduate Student
Senior Research Assistant
Research Scholar
Research Scholar
SKI, Admin. Assistant I
Research Fellow
Sr. Research Technician
Research Scholar
Research Scholar
Postdoctoral Scholar
Research Technician
Sr. Executive Assistant
Lab Alumni
Medical Student Mount Sinai
Assistant Professor- University of Illinois, Chicago
Assistant Member, Molecular Pharmacology Program, SKI; Department of Medicine
Medical Student, Stanford, CA
Clinical Fellow at Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Group Leader, Accutar Biotech
Assistant Professor, Shanghai Jiao Tong University, China
Assistant Professor of Pathology & Cell Biology, Columbia University
Assistant Professor, Yale University
Neuro-Oncologist / MSK HOPP Program
Assistant Professor, Virginia Commonwealth University
Associate Professor, Yale University
Assistant Professor, The Wistar Institute, Philadelphia, PA
Assistant Professor, Tsinghua University, Beijing, China
Member, Institut de Recerca Biomedica, Barcelona
Senior Clinical Research Associate at Veracyte, Inc.
Assistant Professor, U. North Carolina
Professor, Cardiovascular Research Institute, UCSF
Chief Scientific Officer at Accutar Biotec
Professor & Chair, Dept Biochemistry, U. Turku, Finland
Professor of Pathology, Columbia University
Scientist II, Biology at BluePrint Medicines
Postdoctoral Fellow, Broad Institute of MIT & Harvard
Professor of Molecular Biology, Princeton University
Assistant Professor, KAIST, Korea
Professor of Radiation Oncol, Johns Hopkins School of Medicine
Assistant Professor, Cornell University
Patent Attorney, Novartis
Associate Professor of Medicine, UCLA
University of Oviedo, Spain
Student, St. Joseph's Seminary, Washington
Assistant Professor of Pathology, UT Southwestern Med, Dallas
Assistant Professor of Radiation Oncology, U. Pennsylvania
Associate Professor of Pathology, Yale University
Group Leader, (IMP) Institute of Molecular Pathology, Austria
Group Leader, German Cancer Research Center
Assistant Professor, UCLA
Professor, CSIC, Salamanca
Professor, Dana-Farber Cancer Institute, Harvard University
Professor of Cancer Research, Lund University, Sweden
Program Leader, University of Dundee, UK
Research Director, Vall Hebron Institute of Oncology, Barcelona
Student, Stony Brook University
Assoc. Professor of Biochemistry & Medicine, McGill University
Professor, Rockefeller University, New York
Staff Scientist, Hoffmann-La Roche Inc.
Group Leader, CNIO, Madrid
Program Leader, Medical Research Council (MRC), U. Cambridge
Associate Laboratory Member, Research Facilities @ MSKCC
Assoc. Professor of Biochemistry, University of Virginia
Senior Investigator, Lunenfeld Research Institute, U. Toronto
Assistant Professor, Tsinghua University, Beijing
Chief Editor, Nature Cancer @ Nature Publishing
Professor, Baylor College of Medicine, Houston
Postdoctoral Fellow, Broad Institute of MIT & Harvard
Lab Affilations
Achievements
- Director, Sloan Kettering Institute (2014–)
- HHMI Scientific Review Board (2014–)
- HHMI Investigator (1990-2013)
- Fellow, American Association for Cancer Research (AACR) Academy (2016)
- Pezcoller Foundation-AACR International Award for Cancer Research (2016)
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- Charles Rodolphe Brupbacher Prize for Cancer Research (2015)
- National Prize for Research in Biology, Spain (2014)
- American Italian Cancer Foundation Price (2013)
- Prize in Cancer Research, Robert J. and Claire Pasarow Foundation (2011)
- Frontiers Prize in Biomedicine, BBVA Foundation (2008)
- Vilcek Prize, Vilcek Foundation (2006)
- Member, Institute of Medicine (2006)
- Award in Science and Technology, Prince Asturius Foundation (2004)
- Member, National Academy of Sciences (2000)
- Member, American Academy of Arts and Sciences (1999)
- Investigator, Howard Hughes Medical Institute (1990)
- Elucidation of the TGF-beta pathway
Lab News & Events
In June 2019, we bid a farewell to one of our Research Techs, Jessica Hampton. Jessica will be leaving to attend Med school at Stanford University. The Massague Lab wishes her well in all of her future endeavors
March 2019 - Paper Published. During metastasis, cancer cells spread to distant organs where they divide to form microscopic clusters, or micrometastases, that can grow into new tumors. Identification of genes activated in micrometastases can reveal therapeutic targets that can kill cancer cells before they grow into larger tumors that are harder to treat.
