Inside My Lab: Joan Massagué
We are interested in the mechanisms that support tissue homeostasis and cancer metastasis. Focusing on TGFβ as one of the most prevalent signaling pathways in metazoan biology, we are establishing how TGFβ signals control pluripotency and differentiation in stem cells, and homeostasis in mature cells. In addition, we are interested in the genes and pathways that drive metastasis. Ultimately, our goal is to use this basic knowledge to develop innovative cancer treatments.
Joan Massagué, PhD
Executive Director, GMTEC; Director, Sloan Kettering Institute; Member, Cancer Biology & Genetics Program
Professor
Research Focus
Sloan Kettering Institute Director Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.Education
PhD, University of Barcelona- Office Phone: 646-888-2044
- Office Fax: 646-422-0197
- Lab Phone: 646-888-2521
Lab Members
Research Associate
Research Associate
Senior Research Assistant
Research Associate
Graduate Student
Senior Research Assistant
Research Associate
Research Scholar
Research Scholar
Research Scholar
Research Fellow
Sr. Research Technician
Research Technician
Sr. Executive Assistant
Publications
- Basnet H, Tian L, Ganesh K, Huang YH, Macalinao DG, Brogi E, Finley LW, and Massagué J. Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization. Elife (2019); 8: e43627. PMC6440742
- Er, E.E., Valiente, M., Ganesh, K., Agrawal, S., Hu, J., Griscom, B., Rosenblum, M., Boire, A., BRogi, E., Giancotti, F.G., Schachner, M., Malladi, S., and Massagué, J. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastaticcolonization. Nat Cell Biol. 2018 Aug;20(8):966-978. PMC6467203
Selected Achievements
- Fellow, American Association for Cancer Research (AACR) Academy (2016)
- Pezcoller Foundation-AACR International Award for Cancer Research (2016)
- Charles Rodolphe Brupbacher Prize for Cancer Research (2015)
- National Prize for Research in Biology, Spain (2014)
- American Italian Cancer Foundation Price (2013)
- Prize in Cancer Research, Robert J. and Claire Pasarow Foundation (2011)
- Frontiers Prize in Biomedicine, BBVA Foundation (2008)
- Vilcek Prize, Vilcek Foundation (2006)
- Member, Institute of Medicine (2006)
- Award in Science and Technology, Prince Asturius Foundation (2004)
- Member, National Academy of Sciences (2000)
- Member, American Academy of Arts and Sciences (1999)
- Investigator, Howard Hughes Medical Institute (1990)
- Elucidation of the TGF-beta pathway
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