Dissertation Dissection of Transcriptional Programs in Embryonic and Metastatic Stem Cells (2016) Mentor Joan Massagué, PhD Start Year 2010 End Year 2016 Education Tsinghua University Publications Malladi S, Macalinao DG, Jin X, He L, Basnet H, Zou Y, de Stanchina E, Massagué J. (2016) Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT. Cell, 165, 45-60. PMCID: PMC4808520. David CJ, Huang YH, Chen M, Su J, Zou Y, Bardeesy N, Iacobuzio-Donahue CA, Massagué J. (2016) TGF-β Tumor Suppression through a Lethal EMT. Cell, 164, 1015-30. PMCID: PMC4801341 Obenauf AC, Zou Y, Ji AL, Vanharanta S, Shu W, Shi H, Kong X, Bosenberg MC, Wiesner T, Rosen N, Lo RS, Massagué J. (2015) Therapy-induced tumour secretomes promote resistance and tumour progression. Nature, 520, 368-72. PMCID: PMC4507807 Vanharanta S, Marney C, Shu W, Valiente M, Zou Y, Mele A, Darnell R, and Massagué J. (2014) Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer. Elife, 3, 1-24. Morris L, Kaufman A, Gong Y, Ramaswami D, Walsh L, Turcan Ş, Eng S, Kannan K, Zou Y, Peng L, Banuchi V, Paty P, Zeng Z, Vakiani E, Solit D, Singh B, Ganly I, Liau L, Cloughesy T, Mischel P, Mellinghoff I, Chan T. (2013) Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation. Nat Genet, 45, 253-261. PMCID:PMC3729040. Zhang X, Jin X, Malladi S, Zou Y, Wen Y, Brogi E, Smid M, Foekens J, and Massagué J. (2013) Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma. Cell, 154, 1060-1073. PMCID: PMC3974915.
