Research Articles

Basnet H, Tian L, Ganesh K, Huang YH, Macalinao DG, Brogi E, Finley LW, and Massagué J. Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization. Elife (2019); 8: e43627. PMC6440742

David, C.J. and Massagué, J. Contextual determinants of TGFβ action in development, immunity and cancer. Nature Reviews Molecular Cell Biology.  2018 July;19(7):419-435.

Er, E.E., Valiente, M., Ganesh, K., Agrawal, S., Hu, J., Griscom, B.,  Rosenblum, M., Boire, A., BRogi, E., Giancotti, F.G., Schachner, M., Malladi, S., and Massagué, J. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastaticcolonization. Nat Cell Biol. 2018 Aug;20(8):966-978.

Boire, A., Zou, Y., Shieh, J., Macalinao, D., Pentsova, E. and Massagué, J. Complement component 3 adapts the cerebrospinal fluid for leptomeningeal metastasis. Cell 168, 1101-1113 (2017).

Wang, Q., Zou, Y., Nowotschin, S., Kim, S.Y., Soh, C.L., Su, J., Zhang, C., Shu, W., Xi, Q., Huangfu, D., Hadjantonakis, A.K., and Massagué, J. The p53 family coordinates Wnt and nodal inputs in mesendoderm differentiation of embryonic stem cells. Cell Stem Cell 20, 70-86 (2017) PMC5218926

Chen, Q., Boire, A., Jin, X., Valiente, M., Er, E.E., Lopez-Soto, A., Pawta, R., Shah, H., Xu, K., Cross, J.R., and Massagué, J. Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer. Nature 533, 493–498 (2016) PMC5021195

Malladi, S., Macalinao, D., Jin, X., He, L., de Stanchina, E.,, and Massagué, J. Metastatic latency and immune evasion through autocrine inhibition of WNT. Cell 165, 45-60 (2016) PMC4808520

David, C.J., Huang, Y.-H., Chen, M., Su, J., Bardeesy, N., Iacobuzio-Donahue, C., and Massagué, J. TGF-β tumor suppression through a lethal EMT. Cell 164, 1015-30 (2016) PMC4801341

Obenauf, A.C., Zou, Y., Ji, A.L., Vanharanta, S., Shu, W., Shi, H., Kong, X., Bosenberg, M.C., Wiesner, T., Rosen, N., Lo, R.S., and Massagué, J. Therapy induced tumour secretomes promote resistance and tumour progression. Nature 520, 368-372 (2015) PMC4507807

Valiente, M., Obenauf, A.C., Jin, X., Chen, Q., Zhang, X.H.F., Lee, D.J., Chaft, J.E., Kris, M.G., Huse, J.T., Brogi, E. and Massagué, J. Serpins promote cancer cell survival and vascular cooption in brain metastasis. Cell. 2014 Feb 27;156(5):1002–1016.PMC3988473

Review Articles

Massagué, J. and Obenauf, A. Metastatic colonization by circulating tumor cells. Nature 529, 298-306 (2016)