Hu, J., Sánchez-Rivera, F.J., Johnson, G., Wang, Z., Ho, YJ., Ganesh, K., Gan, S., Hampton, J., Zhao, H., Kottapalli, S., De Stanchina, E., Iacobuzio-Donahue, C.A., Pe’er, D., Lowe, S.W., Sun, J., and Massagué, J. STING suppresses the reactivation of dormant metastasis in lung adenocarcinoma. Nature In press.
Paik, P., Luo, J., Ai, N., Kim, R., Ahn, L., Biswas, A., Coker, C., Ma, W., Wong, P., Buonocore, D., Lai, W.V., Chaft, J., Acharyya, S., Massagué, J. and Kris, M. Phase I trial of the TNF-α inhibitor certolizumab plus chemotherapy in stage IV lung adenocarcinomas. Nature Commun. (2022)
Biswas, A.K., Han, S., Tai, Y., Ma, W., Coker, C., Quinn, A., Shakri, A.R., Zhong, T.J., Scholze, H., Lagos, G.G., Mela, A., Manova-Todorova, K., de Stanchina, E., Ferrando, A., Mendelsohn, C., Canoll, P., Yu, H.A., Paik, P., Saqi, A., Shu, C.A., Kris, M.G., Massagué, J. and Acharyya, S. Targeting S100A9-ALDH1A1-retinoic acid signaling to suppress brain relapse in EGFR-mutant lung cancer. Cancer Disc., 19, 262-267 (2022).
Morgani SM, Su J, Nichols J, Massagué J, Hadjantonakis AK. The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos. Elife 30;10 (2021).
Tello-Lafoz M, Srpan K, Sanchez EE, Hu J, Remsik J, Romin Y, Calò A, Hoen D, Bhanot U, Morris L, Boire A, Hsu KC, Massagué J, Huse M, Er EE. Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer. Immunity 7. 54(5):1037-1054 (2021).
Laughney, A.M., Hu, J., Campbell, N.R., Bakhoum, S.F.,Setty, M., Lavallée, V.-P., Xie, Y., Masilonis, I., Carr, A.J., Allaj, V., Mattar, M., Rekhtman, N., Xavier, J., Mazutis, L., Poirier, J.T., Rudin, C.M., Pe’er, D. and Massagué, J. Regenerative lineages and immune-mediated pruning in lung cancer metastasis. Nature Medicine 26, 259-269 (2020).
Ganesh, G., Basnet, H., Laughney, A.M., Kaygusuz, Y., He, L., O’Rourke, K.P., Reuter, V., Huang, Y.-H., Er, E.E., Masilionis, I., Weiser, M.R., Saltz, L.B., Garcia-Aguilar, J., Koche, R., Lowe, S.W., Pe’er, D., Shia, J., and Massagué, J. L1CAM defines the regenerative origin of metastasis initiating cells in colorectal cancer. Nature Cancer 1, 28-44 (2020).
Su, J., M. Morgani, S.M., David, C.J., Wang, Q., Emrah Er, E.E., Huang, Y.-H., Basnet, H., Zou, Y., Shu, W., Hendrickson, R.C., Soni, R.K., Hadjantonakis, A.-K. and Massagué, J. TGF-β orchestrates fibrogenic and developmental EMTs via RAS effector RREB1. Nature 577, 566–571 (2020)
Huang, Y.-H., Hu, J., Chen, F., Lecomte, N., Basnet, H., David, C.J., Witkin, M.D., Allen, P., Leach, S.D., Hollmann, T.J., Iacobuzio-Donahue, C.A., Massagué, J. ID1 mediates escape from TGF-β tumor suppression in pancreatic cancer. Cancer Disc. 10, 142-157 (2020)
Reviews:
Lee, J.H. and Massagué, J. TGF-β in developmental and fibrogenic EMTs. Sem. Cancer Biol. 86, 136-145 (2022).
Ganesh K, Massagué J. Targeting metastatic cancer. Nat Med (1):34-44 (2021).
Massagué J, Ganesh K. Metastasis-Initiating Cells and Ecosystems. Cancer Discov (4):971-994 (2021).
Batlle, E. and Massagué, J. TGFβ signaling in immunity and cancer. Immunity 16;50(4):924-940 (2019)
