Chemical Biology Program
The Gabriela Chiosis Lab
Research

Professor
The goal of my program is to investigate the nature of chronic stress as it occurs in numerous diseases and aging. Our approach takes advantage of the way nature has evolved to control such stresses, and that is by a unique usage of the chaperome, referred to here as the chronic stress chaperome (CSC). The CSC is structurally, dynamically and functionally distinct from the housekeeping chaperome, and my lab has pioneered an approach to take advantage of such feature. By using innovative methods, we develop small molecule chemical tool sets specifically targeted to the CSC; these act as “sensors” of the CSC and, in turn, of the chronic stress-associated proteome. By the use of these unique tool sets we aim to understand, diagnose, and treat cellular processes associated with chronic stress.
Research Projects

Chiosis Lab - October 2013
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Publications
People

Gabriela Chiosis, PhD
Professor
- The Chiosis lab uses a unique chemical biology approach to understand, diagnose, and treat cellular processes associated with chronic molecular stress, with the ultimate goal of developing novel therapeutic options for use in the clinic.
- PhD, Columbia University
- chiosisg@mskcc.org
- Email Address
- 646-888-2235
- Office Phone
Members

Senior Research Scientist

Senior Research Scientist

Research Associate

Research Scholar

Research Fellow

Research Scholar

Research Fellow

Research Technician
Administrative Assistant

Research Fellow - Medicinal Chemist

Research Scholar - Medicinal Chemist
Lab Alumni

Research Fellow

Graduate Student

Research Scholar

Research Scholar

Research Scholar

Research Technician

Research Technician

Research Scholar

Research Fellow
Research Scholar

Research Technician

Research Fellow

Research Associate

Research Fellow
Research Technician
Lab Affilations
Achievements
- AACR – Cancer Research and Prevention Career Development Award in Translational Lung Cancer Research, in Memory of Duffy Wall
- Susan G. Komen Breast Cancer Translational Research Award
- Frederick R. Adler Chair for Junior Faculty
- Award for Drug Discovery Research for Frontotemporal Dementia
- Top 5 percent cited author in Biology and Biochemistry 2010 (analysis by Thomson Reuters)
Read more
- Translated from bench-to-bedside the Hsp90 inhibitor PU-H71 and the non-invasive companion diagnostic 124I-PU-H71 PET assay
Lab News & Events
Upcoming event
Targeted Therapeutics for Triple Negative Breast Cancer
This seminar will be conducted by Zoom Webinar.
Open Positions
Get in Touch
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Lab Head Email
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Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Gabriela Chiosis discloses the following relationships and financial interests:
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Samus Therapeutics LLC
Fiduciary Role/Position; Intellectual Property Rights; Ownership / Equity Interests
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.
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