Student Publications

Student Publications

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Su J, Morgani SM, David CJ, Wang Q, Er EE, Huang YH, Basnet H, Zou Y, Shu W, Soni RK, Hendrickson RC, Hadjantonakis AK, Massague J. (2020) TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1. Nature. 578.

Keith J, Dong Q, Sorbara MT, Becattini S, Sia JK, Gjonbalaj M, Seok R, Leiner I, Littmann E, Pamer EG. (2020) Impact of antibiotic-resistant bacteria in the mouse intestine on immune activation and Clostridioides difficile infection. Infect Immun, pii: IAI.00362-19. [Epub ahead of print]

Gjonbalaj M, Keith JW, Do MH, Hohl TM, Pamer EG, Becattini S. Antibiotic degradation by commensal microbes shields pathogens.(2020) Infect Immun., pii: IAI.00012-20 [Epub ahead of print]

Mao N, Gao D, Hu W, Gadal S, Hieronymus H, Wang S, Sullivan P, Zhang Z, Choi D, Rosen N, Sawyers CL, Gopalan A, Chen Y, Carver BS. (2020) Oncogenic ERG represses PI3K signaling through down-regulation of IRS2. Cancer Res. pii: canres.1394.2019 [Epub ahead of print]

Vorselen D, Wang Y, de Jesus MM, Shah PK, Footer MJ, Huse M, Cai W, Theriot JA. (2020) Microparticle traction force microscopy reveals subcellular force exertion patterns in immune cell-target interactions.Nat Commun 11, PMCID:PMC6946705

Santich BH, Park JA, Tran H, Guo HF, Huse M, Cheung NV (2020) Interdomain spacing and spatial configuration drive the potency of IgG-[L]-scFv T cell bispecific antibodies.Sci Transi Med. 534, pii: eaax1315

Temprine K, Campbell NR, Huang R, Langdon EM, Simon-Vermot T, Mehta K, Clapp A, Chipman M, White RM. (2020) Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance. Science Signal.

Tischler BY, Tosini NL, Cramer RA, Hohl TM. (2020) Platelets are critical for survival and tissue integrity during murine pulmonary Aspergillus fumigatus infection. Plos Pathog. 5

Zhang Z, Zhou C, Li X, Barnes SD, Deng S, Hoover E, Chen CC, Lee YS, Zhang Y, Wang C, Metang LA, Wu C, Tirado CR, Johnson NA, Wongvipat J, Navrazhina K, Cao Z, Choi D, Huang D, Huang CH, Linton E, Chen X, Liang Y, Mason CE, de Stanchina E, Abida W, Lujambio A, Li S, Lowe SW, Mendell JT, Malladi VS, Sawyers CL, Mu P. (2020) Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation. Cancer Cell 34, 584-598

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Adams NM, Geary CD, Santosa EK, Lumaquin D, Le Luduec JB, Sottile R, van der Ploeg K, Hsu J, Whitlock BM, Jackson BT, Weizman OE, Huse M, Hsu KC, Sun JC. (2019) Cytomegalovirus Infection Drives Avidity Selection of Natural Killer Cells. Immunity. pii: S1074-7613(19)30189-X. [Epub ahead of print].

Dong H, Adams NM, Xu Y, Cao J, Allan DSJ, Carlyle JR, Chen X, Sun JC, Glimcher LH; (2019) The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc. Nat Immunol. PMCID: PMC6588410 [Available on 2019-11-13].

Minuesa G, Albanese SK, Xie W, Kazansky Y, Worroll D, Chow A, Schurer A, Park SM, Rotsides CZ, Taggart J, Rizzi A, Naden LN, Chou T, Gourkanti S, Cappel D, Passarelli MC, Fairchild L, Adura C, Glickman JF, Schulman J, Famulare C, Patel M, Eibl JK, Ross GM, Bhattacharya S, Tan DS, Leslie CS, Beuming T, Patel DJ, Goldgur Y, Chodera JD, Kharas MG; (2019) Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nat Commun. 10, 2691. PMCID:PMC6584500.

Vardhana SA, Arnold PK, Rosen BP, Chen Y, Carey BW, Huangfu D, Fontaine CC, Thompson CB, Finley LWS (2019) Glutamine independence is a selectable feature of pluripotent stem cells. Nat Metab. 1, 676-687. PMCID: PMC6737941 [Available on 2020-01-08]

Osmanbeyoglu HU, Shimizu F, Rynne-Vidal A, Alonso-Curbelo D, Chen HA, Wen HY, Yeung TL, Jelinic P, Razavi P, Lowe SW, Mok SC, Chiosis G, Levine DA, Leslie CS. (2019) Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers. Nat Commun. 10, 4369. PMCID: PMC6761109

Shi Y, Lim SK, Liang Q, Iyer SV, Wang HY, Wang Z, Xie X, Sun D, Chen YJ, Tabar V, Gutin P, Williams N, De Brabander JK, Parada LF. (2019) Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. doi: 10.1038/s41586-019-0993-x. [Epub ahead of print].

Hamieh M, Dobrin A, Cabriolu A, van der Stegen SJC, Giavridis T, Mansilla-Soto J, Eyquem J, Zhao Z, Whitlock BM, Miele MM, Li Z, Cunanan KM, Huse M, Hendrickson RC, Wang X, Rivière I, Sadelain M. (2019) CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape. Nature. 568, 112-116.

Lee Y, Hamann JC, Pellegrino M, Durgan J, Domart MC, Collinson LM, Haynes CM, Florey O, Overholtzer M. (2019) Entosis Controls a Developmental Cell Clearance in C. elegans. Cell Rep. 26, 3212-3220.

Hamann JC, Kim SE, Overholtzer M. (2019) Methods for the Study of Entotic Cell Death. Methods Mol Biol. 1880, 447-454.

Taylor J, Sendino M, Gorelick AN, Pastore A, Chang MT, Penson AV, Gavrila EI, Stewart C, Melnik EM, Herrejon Chavez F, Bitner L, Yoshimi A, Lee SC, Inoue D, Liu B, Zhang XJ, Mato AR, Dogan A, Kharas MG, Chen Y, Wang D, Soni RK, Hendrickson RC, Prieto G, Rodriguez JA, Taylor BS, Abdel-Wahab O. (2019) Altered nuclear export signal recognition as a driver of oncogenesis. Cancer Discov. 9, 1452-1467.

Jelcic M, Enyedi B, Niethammer P. (2019) Quantitative Imaging of Endogenous and Exogenous H2O2 Gradients in Live Zebrafish Larvae. Methods Mol Biol. 1982 , 283-299.

Kansler ER, Li MO. (2019) Innate lymphocytes-lineage, localization and timing of differentiation. Cell Mol Immunol. doi: 10.1038/s41423-019-0211-7. [Epub ahead of print].

Karasu ME, Bouftas N, Keeney S, Wassmann K. (2019) Cyclin B3 promotes anaphase I onset in oocyte meiosis. J Cell Biol. 218, 1265-1281. PMCID: PMC6446836. [Available on 2019-10-01].

Boekhout M, Karasu ME, Wang J, Acquaviva L, Pratto F, Brick K, Eng DY, Xu J, Camerini-Otero RD, Patel DJ, Keeney S. (2019) REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks. Mol Cell. pii: S1097-2765(19)30227-8. [Epub ahead of print].

Loizou E, Banito A, Livshits G, Ho YJ, Koche RP, Sanchez-Rivera FJ, Mayle A, Chen CC, Kinalis S, Bagger FO, Kastenhuber ER, Durham BH, Lowe SW. (2019) A gain-of-function p53 mutant oncogene promotes cell fate plasticity and myeloid leukemia through the pluripotency factor Foxh1. Cancer Discov. pii: CD-18-1391

Dinh TA, Jewell ML, Kanke M, Francisco A, Sritharan R, Turnham RE, Lee S, Kastenhuber ER, Wauthier E, Guy CD, Yeung RS, Lowe SW, Reid LM, Scott JD, Diehl AM, Sethupathy P. (2019) MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma. Cell Mol Gastroenterol Hepatol. 7, 803-817. PMID: 30763770.

Moon SH, Huang CH, Houlihan SL, Regunath K, Freed-Pastor WA, Morris JP, Tschaharganeh DF, Kastenhuber ER, Barsotti AM, Culp-Hill R, Xue W, Ho YJ, Baslan T, Li X, Mayle A, de Stanchina E, Zender L, Tong DR, D’Alessandro A, Lowe SW, Prives C. (2019) p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. Cell. 176, 564-580. PMCID: PMC6483089.

Konopacki C, Pritykin Y, Rubtsov Y, Leslie CS, Rudensky AY. (2019) Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function. Nat Immunol. 20, 232-242.

Kuhn NF, Purdon TJ, van Leeuwen DG, Lopez AV, Curran KJ, Daniyan AF, Brentjens RJ; (2019) CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response.Cancer Cell. 35, 473-488. PMCID: PMC6428219.

Li X, Ventura A. (2019) ALK7 Erects a Suppressive Barrier to Tumor Progression and Metastasis. Dev Cell. 49, 304-305.

Li QV, Dixon G, Verma N, Rosen BP, Gordillo M, Luo R, Xu C, Wang Q, Soh CL, Yang D, Crespo M, Shukla A, Xiang Q, Dündar F, Zumbo P, Witkin M, Koche R, Betel D, Chen S, Massagué J, Garippa R, Evans T, Beer MA, Huangfu D. (2019) Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation. Nat Genet. 51, 999-1010.

Basnet H, Tian L, Ganesh K, Huang YH, Macalinao DG, Brogi E, Finley LW, Massagué J. (2019) Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization. Elife. 8, pii: e43627. PMCID: PMC6440742.

Yen WF, Sharma R, Cols M, Lau CM, Chaudhry A, Chowdhury P, Yewdell WT, Vaidyanathan B, Sun A, Coffre M, Pucella JN, Chen CC, Jasin M, Sun JC, Rudensky AY, Koralov SB, Chaudhuri J. (2019) Distinct Requirements of CHD4 during B Cell Development and Antibody Response. Cell Rep. 27, 1472-1486.

Pucella JN, Cols M, Yen WF, Xu S, Chaudhuri J. (2019) The B Cell Activation-Induced miR-183 Cluster Plays a Minimal Role in Canonical Primary Humoral Responses. J Immunol. pii: ji1800071.

Riegman M, Bradbury MS, Overholtzer M. (2019) Population Dynamics in Cell Death: Mechanisms of Propagation. Trends Cancer. 5, 558-568.

Smith RC, Tabar V. (2019) Constructing and Deconstructing Cancers using Human Pluripotent Stem Cells and Organoids. Cell Stem Cell . 24, 12-24. PMCID: PMC6516073

Phillips RE, Yang Y, Smith RC, Thompson BM, Yamasaki T, Soto-Feliciano YM, Funato K, Liang Y, Garcia-Bermudez J, Wang X, Garcia BA, Yamasaki K, McDonald JG, Birsoy K, Tabar V, Allis CD. (2019) Target identification reveals lanosterol synthase as a vulnerability in glioma. Proc Natl Acad Sci USA. pii: 201820989. [Epub ahead of print].

Nicolas L, Cols M, Smolkin R, Fernandez KC, Yewdell WT, Yen WF, Zha S, Vuong BQ, Chaudhuri J. (2019) Cutting Edge: ATM Influences Germinal Center Integrity. J Immunol. pii: ji1801033. [Epub ahead of print].

Grommes C, Tang SS, Wolfe J, Kaley TJ, Daras M, Pentsova EI, Piotrowski AF, Stone J, Lin A, Nolan CP, Manne M, Codega P, Campos C, Viale A, Thomas AA, Berger MF, Hatzoglou V, Reiner AS, Panageas KS, DeAngelis LM, Mellinghoff IK; (2019) Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma. Blood. 133, 436-445. PMCID: PMC6356986.

Tischler BY, Hohl TM. (2019) Menacing Mold: Recent Advances in Aspergillus Pathogenesis and Host Defense. J Mol Biol. pii: S0022-2836(19)30176-7.

Miller AN, Vaisey G, Long SB. (2019) Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin. eLife. 8. pii: e43231. PMCID: PMC6342527.

Woods B, Chen W, Chiu S, Marinaccio C, Fu C, Gu L, Bulic M, Yang Q, Zouak A, Jia S, Suraneni PK, Xu K, Levine RL, Crispino JD, Wen QJ. (2019) Activation of JAK/STAT signaling in megakaryocytes sustains myeloproliferation in vivo. Clin Cancer Res. pii: clincanres.4089.2018. [Epub ahead of print].

Adams EJ, Karthaus WR, Hoover E, Liu D, Gruet A, Zhang Z, Cho H, DiLoreto R, Chhangawala S, Liu Y, Watson PA, Davicioni E, Sboner A, Barbieri CE, Bose R, Leslie CS, Sawyers CL (2019) FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes. Nature. doi: 10.1038/s41586-019-1318-9.

Huang YH, Hu J, Chen F, Lecomte N, Basnet H, David CJ, Witkin MD, Allen PJ, Leach SD, Hollmann TJ, Iacobuzio-Donahue CA, Massague J. (2019) ID1 mediates escape from TGF-β tumor suppression in pancreatic cancer. Cancer Discov.

Inoue D, Chew GL, Liu B, Michel BC, Pangallo J, DAvino AR, Hitchman T, North K, Bitner L, Block A, Moore AR, Yoshimi A, Escobar-Hoyos L, Cho H, Penson A, Lu SX, Taylor J, Chen Y, Kadoch C, Abdel-Wahab o, Bradley RK. (2019) Spliceosomal disruption of the non-canonical BAF complex in cancer. Nature.574, 432-436.

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Ruscetti M, Leibold J, Bott MJ, Fennell M, Kulick A, Salgado NR, Chen CC, Ho YJ, Sanchez-Rivera FJ, Feucht J, Baslan T, Tian S, Chen HA, Romesser PB, Poirier JT, Rudin CM, de Stanchina E, Manchado E, Sherr CJ, Lowe SW. (2018) NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. Science. 362, 1416-1422.

Feucht J, Sun J, Eyquem J, Ho YJ, Zhao Z, Leibold J, Dobrin A, Cabriolu A, Hamieh M, Sadelain M. (2018) Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency. Nat Med. [Epub ahead of print].

Smith RC, Tabar V. (2018) Constructing and Deconstructing Cancers using Human Pluripotent Stem Cells and Organoids. Cell Stem Cell pii: S1934-5909, 30548-4. [Epub ahead of print].

Wang W, Liu W, Fidler T, Wang Y, Tang Y, Woods B, Welch C, Cai B, Silvestre-Roig C, Ai D, Yang YG, Hidalgo A, Soehnlein O, Tabas I, Levine RL, Tall AR, Wang N. (2018) Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 V617F Mice. Circ Res. 123, e35-e47.

Ruff EF, Muretta JM, Thompson AR, Lake EW, Cyphers S, Albanese SK, Hanson SM, Behr JM, Thomas DD, Chodera JD, Levinson NM. (2018) A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation. Elife 7, e32766.

Intlekofer AM, Shih AH, Wang B, Nazir A, Rustenburg AS, Albanese SK, Patel M, Famulare C, Correa FM, Takemoto N, Durani V, Liu H, Taylor J, Farnoud N, Papaemmanuil E, Cross JR, Tallman MS, Arcila ME, Roshal M, Petsko GA, Wu B, Choe S, Konteatis ZD, Biller SA, Chodera JD, Thompson CB, Levine RL, Stein EM. (2018) Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations. Nature 559, 125-129.

Hauser K, Negron C, Albanese SK, Ray S, Steinbrecher T, Abel R, Chodera JD, Wang L. (2018) Predicting resistance of clinical Abl mutations to targeted kinase inhibitors using alchemical free-energy calculations. Commun Biol 1, pii: 70. PMCID: PMC6110136

Rajshekar S, Yao J, Arnold PK, Payne SG, Zhang Y, Bowman TV, Schmitz RJ, Edwards JR, Goll M. (2018) Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome. Elife. pii: e39658. PMCID: PMC6261255 

Callahan SJ, Tepan S, Zhang YM, Lindsay H, Burger A, Campbell NR, Kim IS, Hollmann TJ, Studer L, Mosimann C, White RM. (2018) Cancer modeling by Transgene Electroporation in Adult Zebrafish (TEAZ). Dis Model Mech. pii: dmm.034561 [Epub ahead of print] 

Zhang YM, Zimmer MA, Guardia T, Callahan SJ, Mondal C, Di Martino J, Takagi T, Fennell M, Garippa R, Campbell NR, Bravo-Cordero JJ, White RM. (2018) Distant Insulin Signaling Regulates Vertebrate Pigmentation through the Sheddase Bace2. Dev Cell. pii: S1534-5807(18)30357-5 [Epub ahead of print]

Casey E, Bournazos S, Mo G, Mondello P, Tan KS, Ravetch JV, Scheinberg DA. (2018). A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies. Leukemia. 32, 547-549. PMCID: PMC5803448

Serganova I, Cohen IJ, Vemuri K, Shindo M, Maeda M, Mane M, Moroz E, Khanin R, Satagopan J, Koutcher JA, Blasberg R. (2018) LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response. PLoS One 13, e0203965.

Feng W, Jasin M. (2018) Homologous Recombination and Replication Fork Protection: BRCA2 and More! Cold Spring Harb Symp Quant Biol. pii: 035006.

Chen CC, Feng W, Lim PX, Kass EM, Jasin M. (2018) Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer. Annu Rev Cancer Biol. 2, 313-336. PMCID: PMC619349.

Gala K, Li Q, Sinha A, Razavi P, Dorso M, Sanchez-Vega F, Chung YR, Hendrickson R, Hsieh J, Berger M, Schultz N, Pastore A, Abdel-Wahab O, Chandarlapaty S. (2018) KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function. Oncogene. [Epub ahead of print]

Hawk MA, Gorsuch CL, Fagan P, Lee C, Kim SE, Hamann JC, Mason JA, Weigel KJ, Tsegaye MA, Shen L, Shuff S, Zuo J, Hu S, Jiang L, Chapman S, Leevy WM, DeBerardinis RJ, Overholtzer M, Schafer ZT. (2018) RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells. Nat Cell Biol. 20, 272-284.

Moore AR, Ran L, Guan Y, Sher JJ, Hitchman TD, Zhang JQ, Hwang C, Walzak EG, Shoushtari AN, Monette S, Murali R, Wiesner T, Griewank KG, Chi P, Chen Y. (2018) GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma. Cell Rep. 22, 2455-2468.

Kavaler J, Duan H, Aradhya R, de Navas LF, Joseph B, Shklyar B, Lai EC. (2018) miRNA suppression of a Notch repressor directs non-neuronal fate in Drosophila mechanosensory organs. J Cell Biol 217, 571-583. PMCID:PMC5800810

Joseph B, Kondo S, Lai EC. (2018) Short cryptic exons mediate recursive splicing in Drosophila. Nat Struct Ml Biol. 25, 365-371.

Zafra MP, Schatoff EM, Katti A, Foronda M, Breinig M, Schweitzer AY, Simon A, Han T, Goswami S, Montgomery E, Thibado J, Kastenhuber ER, Sánchez-Rivera FJ, Shi J, Vakoc CR, Lowe SW, Tschaharganeh DF, Dow LE. (2018) Optimized base editors enable efficient editing in cells, organoids and mice. Nat Biotechnol. PMID: 29969439 doi: 10.1038/nbt.4194. [Epub ahead of print]

Keith JW, Pamer EG. (2018) Enlisting commensal microbes to resist antibiotic-resistant pathogens. J Exp Med, pii: jem.20180399. [Epub ahead of print].

Klein ME, Kovatcheva M, Davis LE, Tap WD, Koff A. (2018) CDK4/6 Inhibitors: The Mechanism of Action May Not Be as Simple as Once Thought. Cancer Cell. [Epub ahead of print]

Klein ME, Dickson MA, Antonescu C, Qin LX, Dooley SJ, Barlas A, Manova K, Schwartz GK, Crago AM, Singer S, Koff A, Tap WD. (2018) PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence. Oncogene. [Epub ahead of print]

Azizi E, Carr AJ, Plitas G, Cornish AE, Konopacki C, Prabhakaran S, Nainys J, Wu K, Kiseliovas V, Setty M, Choi K, Fromme RM, Dao P, McKenney PT, Wasti RC, Kadaveru K, Mazutis L, Rudensky AY, Pe’er D. (2018) Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment. Cell, pii: S0092-8674(18)30723-2. PMID: 29961579 [Epub ahead of print]

Verma N, Pan H, Doré LC, Shukla A, Li QV, Pelham-Webb B, Teijeiro V, González F, Krivtsov A, Chang CJ, Papapetrou EP, He C, Elemento O, Huangfu D. (2018) TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells. Nat Genet, 50, 83-95. PMCID: PMC5742051 [Available on 2018-06-04]

Yang TT, Chong WM, Wang WJ, Mazo G, Tanos B, Chen Z, Tran TMN, Chen YD, Weng RR, Huang CE, Jane WN, Tsou MB, Liao JC (2018) Super-resolution architecture of mammalian centriole distal appendages reveals distinct blade and matrix functional components. Nat Commun. 9, 2023. PMCID: PMC5964178

Hobbs GS, Hanasoge Somasundara AV, Kleppe M, Litvin R, Arcila M, Ahn J, McKenney AS, Knapp K, Ptashkin R, Weinstein H, Heinemann MH, Francis J, Chanel S, Berman E, Mauro M, Tallman MS, Heaney ML, Levine RL, Rampal RK. (2018) Hsp90 inhibition disrupts JAK-STAT signaling and leads to reductions in splenomegaly in patients with myeloproliferative neoplasms. Haematologica. 103, e5-e9. PMCID: PMC5777196

McKenney AS, Lau AN, Somasundara AVH, Spitzer B, Intlekofer AM, Ahn J, Shank K, Rapaport FT, Patel MA, Papalexi E, Shih AH, Chiu A, Freinkman E, Akbay EA, Steadman M, Nagaraja R, Yen K, Teruya-Feldstein J, Wong KK, Rampal R, Heiden MGV, Thompson CB, Levine RL. (2018) JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition. J Clin Invest. 128, 789-804. PMCID: PMC5785272

Wu Z, Santich BH, Liu H, Liu C, Cheung NV. (2018) Targeting Intracellular Antigens with pMHC-Binding Antibodies: A Phage Display Approach. Methods Mol Biol. 1701, 255-269.

Ahmed M, Lopez-Albaitero A, Pankov D, Santich BH, Liu H, Yan S, Xiang J, Wang P, Hasan AN, Selvakumar A, O’Reilly RJ, Liu C, Cheung NV. (2018) TCR-mimic bispecific antibodies targeting LMP2A show potent activity against EBV malignancies. JCI Insight. 3, pii: 97805. PMCID: PMC5916246 [Epub ahead of print]

Vaisey G, Long SB. (2018) An allosteric mechanism of inactivation in the calcium-dependent chloride channel BEST1. J Gen Physiol. pii: jgp.201812190.

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Rapp M, Lau CM, Adams NM, Weizman OE, O’Sullivan TE, Geary CD, Sun JC; Core-binding factor ß and Runx transcription factors promote adaptive natural killer cell responses.; Science immunology; 2017; 2(18);

Weizman OE, Adams NM, Schuster IS, Krishna C, Pritykin Y, Lau C, Degli-Esposti MA, Leslie CS, Sun JC, O’Sullivan TE; ILC1 Confer Early Host Protection at Initial Sites of Viral Infection.; Cell; 2017; 171(4):795-808.e12;

Rapp M, Lau CM, Adams NM, Weizman OE, O’Sullivan TE, Geary CD, Sun JC. (2017) Core-binding factor β and Runx transcription factors promote adaptive natural killer cell responses. Sci Immunol 2.

Gardner EE, Lok BH, Schneeberger VE, Desmeules P, Miles LA, Arnold PK, Ni A, Khodos I, de Stanchina E, Nguyen T, Sage J, Campbell JE, Ribich S, Rekhtman N, Dowlati A, Massion PP, Rudin CM, Poirier JT. (2017) Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis. Cancer Cell 31, 286-299. PMCID: PMC5313262 [Available on 2018-02-13]

Sansone P, Berishaj M, Rajasekhar VK, Ceccarelli C, Chang Q, Strillacci A, Savini C, Shapiro L, Bowman R, Mastroleo C, De Carolis S, Daly L, Benito-Martin A, Perna F, Fabbri N, Healey JH, Spisni E, Cricca M, Lyden D, Bonafé M, Bromberg J. (2017) Evolution of cancer stem-like cells in endocrine-resistant metastatic breast cancers is mediated by stromal microvesicles. Cancer Res. [Epub ahead of print]

Bowman RL, Wang Q, Carro A, Verhaak RG, Squatrito M. (2017) GlioVis data portal for visualization and analysis of brain tumor expression datasets. Neuro Oncol. 19, 139-141. PMCID: PMC5193031 [Available on 2018-01-01]

Kim IS, Heilmann S, Kansler ER, Zhang Y, Zimmer M, Ratnakumar K, Bowman RL, Simon-Vermot T, Fennell M, Garippa R, Lu L, Lee W, Hollmann T, Xavier JB, White RM. (2017) Microenvironment-derived factors driving metastatic plasticity in melanoma. Nat Commun. 8, 14343. PMCID: PMC5309794

Cohen I, Blasberg R. (2017) Impact of the Tumor Microenvironment on Tumor-Infiltrating Lymphocytes: Focus on Breast Cancer. Breast Cancer (Auckl) 11. PMCID: PMC5617083

Feng W, Jasin M. (2017) BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination. Nat Commun. 8, 525. PMCID: PMC5597640

Vanoli F, Tomishima M, Feng W, Lamribet K, Babin L, Brunet E, Jasin M. (2017) CRISPR-Cas9-guided oncogenic chromosomal translocations with conditional fusion protein expression in human mesenchymal cells. Proc Natl Acad Sci U S A. 114, 3696-3701. PMCID: PMC5389291 [Available on 2017-10-04]

Hamann JC, Overholtzer M. (2017) Entosis enables a population response to starvation. Oncotarget 8, 57934-57935. PMCID: PMC5601622

Hamann JC, Surcel A, Chen R, Teragawa C, Albeck JG, Robinson DN, Overholtzer M. (2017) Entosis Is Induced by Glucose Starvation. Cell Rep. 20, 201-210. PMCID: PMC5559205

Hamann J, Overholtzer M. (2017) Killing me softly: microparticles target deformable cells. Cell Res. 26, 637-8. PMCID: PMC4897184 [Available on 2017-06-01]

Durgan J, Tseng YY, Hamann JC, Domart MC, Collinson L, Hall A, Overholtzer M, Florey O. (2017) Mitosis can drive cell cannibalism through entosis. Elife 6, pii: e27134. PMCID: PMC5505699

Spraggon L, Martelotto LG, Hmeljak J, Hitchman TD, Wang J, Wang L, Slotkin EK, Fan PD, Reis-Filho JS, Ladanyi M. (2017) Generation of conditional oncogenic chromosomal translocations using CRISPR-Cas9 genomic editing and homology-directed repair. J Pathol. 242, 102-112. PMCID: PMC5397343 [Available on 2018-05-01]

Jelcic M, Enyedi B, Xavier JB, Niethammer P. (2017) Image-Based Measurement of H2O2 Reaction-Diffusion in Wounded Zebrafish Larvae. Biophys J. 112, 2011-2018. PMCID:PMC5425381 [Available on 2018-05-09]

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