Office Phone 646-888-2046 Office Fax 646-422-0231 Lab Phone 646-888-2059 Email [email protected] Dissertation Investigation of Tumor Cell Intrinsic and Extrinsic Regulators of Pancreatic Neuroendocrine Tumorigenesis (2013) Mentor Johanna Joyce, PhD Start Year 2007 End Year 2013 Education Massachusetts Institute of Technology Publications Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA. (2014) Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix. Genes Dev., 28, 2134-50. PMCID: PMC4180975. Hunter K, Palermo C, Kester J, Simpson K, Li J, Tang L, Klimstra D, Vlodavsky I, Joyce J. (2014) Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors. Oncogene, 3, 1799-1808. Hunter K, Quick M, Sadanandam A, Hanahan D, Joyce J. (2013) Identification and characterization of poorly differentiated invasive carcinomas in a mouse model of pancreatic neuroendocrine tumorigenesis. PLoS One, 8, 1-11. Pyonteck S, Gadea B, Wang H, Gocheva V, Hunter K, Tang L, Joyce J. (2012) Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development. Oncogene, 31, 1459-1467. Gocheva V, Wang H, Gadea B, Shree T, Hunter K, Garfall A, Berman T, Joyce J. (2010) IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion. Genes Dev, 24, 241-255. Williams BR, Prabhu VR, Hunter KE, Glazier CM, Whittaker CA, Housman DE, Amon A. (2008) Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells. Science. 322, 703-9. PMCID: PMC2701511 View a full listing of Karen Hunter Cohn’s journal articles.
