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In the Lab

Drug Combination Could Boost the Effectiveness of Immunotherapy against Pancreatic Cancer

By Matthew Tontonoz

Studies conducted in mice reveal a potential way to breach the defenses of pancreatic cancer tumors.

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A drawing of a pancreatic tumor represented as a barren landscape, blood vessels as rivers, and immune cells as ships with ammunition.

In the Lab

Shape-Shifting Stem Cells Are Key to Cancer Metastasis and Immune Evasion

By Matthew Tontonoz

By assuming primitive regenerative identities, cancer cells gain the adaptability they need to establish tumors in new parts of the body.

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An illustration of lung develop alongside tumor evolution

Feature

Researchers Find that Vitamin B6 Contributes to Survival of Acute Myeloid Leukemia Cells

By Julie Grisham

This research marks the first time researchers have found a connection between vitamin B6 and cancer.

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Cancer biologist Scott Lowe at a white board

In the Lab

What Does Cancer Metastasis Have to Do with Wound Healing? More than You Might Think

By Matthew Tontonoz

Scientists are learning that — in a literal sense — metastasis is wound healing gone wrong.

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Graphical representation of cells leaking into bloodstream

In the Lab

Mind the Gap: Scientists Learn How Cells Make and Repair Tight Connections

By Matthew Tontonoz

New findings from researchers at the Sloan Kettering Institute provide insight into a fundamental biological process called the epithelial-mesenchymal transition.

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Epithelial cells

In the Lab

Why KRAS Inhibitors for Lung Cancer Stop Working (and What Can Be Done about It)

By Matthew Tontonoz

Recently developed targeted drugs used to treat lung cancer are only partially effective. Scientists now know why.

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A picture of KRAS-mutated lung cancer cells

Q&A

Peering at Biological Molecules: A Conversation with Structural Biology Chair Christopher Lima

By Julie Grisham

Seeing Biological Molecules at the Atomic Level: At Work with Christopher Lima, Structural Biology Chair.

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Structural biologist Christopher Lima

Michel Sadelain Awarded 2019 Inserm International Prize

Dr. Sadelain received the award for his research on chimeric antigen receptors (CARs) and their use in providing tailored cancer treatment to patients.

  • Tuesday, December 17, 2019

In the News

ASH 2019 Roundup: The Latest on CAR T, New Treatments for CLL, and Using Genes to Predict a Common Side Effect

By Matthew Tontonoz

Read highlights of research presented by MSK scientists at the annual ASH meeting.

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A crowd of people entering a large hall

Finding

Many Mutations Detected in Liquid Biopsy Tests Do Not Come from Cancer Cells, an MSK Study Finds

By Matthew Tontonoz

The new findings suggest the need for caution when interpreting the results from these tests.

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Pedram Razavi, Jorge Reis-Filho, and Bob Li