Structural Biology Program
The Nikola Pavletich Lab
Our research group is interested in understanding, at the structural and mechanistic levels, the maintenance of genomic integrity and the control of cell growth, both of which figure prominently in cancer. In the area of growth control, our recent work is focused on the mTOR pathway that controls multiple aspects of cell growth and homeostasis. Our work on genomic integrity ranges from the Fanconi Anemia pathway, which responds to DNA interstrand crosslinks, to the ATR and ATM checkpoint kinases that coordinate the cell’s response to replication stress and DNA double-strand breaks, respectively. Common to these genomic integrity pathways is eventual repair by homologous recombination, a process that has been a longstanding focus of our research.
Nikola P. Pavletich, PhD
- The Pavletich laboratory studies the structural biology of pathways that control cell growth and maintain the integrity of the genome.
- PhD, Johns Hopkins University
Get in Touch
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Nikola P. Pavletich discloses the following relationships and financial interests:
No disclosures meeting criteria for time period
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.