Immunology Program
The Alexander Rudensky Lab
Research

Professor
Our research is focused on understanding the molecular mechanisms governing the differentiation and function of CD4 T lymphocytes and their role in immunity and tolerance. Major areas of interest include: the molecular and cellular mechanisms governing the differentiation and function of regulatory T cells; the roles these cells play in control of autoimmunity, tumor immunity, and immunity to infections, and in the maintenance of immune homeostasis at environmental interfaces. We are particularly interested in understanding the role of the forkhead family transcription factor Foxp3 in establishing and maintaining immune homeostasis; and in the plasticity of regulatory T cell transcriptional and functional programs and the molecular mechanisms of regulatory T cell lineage stability.

Featured News



Publications
People

Alexander Rudensky, PhD
Chair, Immunology Program, SKI; Director, Ludwig Center at MSK
Professor
- Immunology Program Chair Alexander Rudensky focuses on immunological tolerance and the differentiation and function of T cells.
- PhD, Gabrichevsky Institute for Microbiology and Epidemiology
- [email protected]
- Email Address
- 646-888-3109
- Office Phone
Members

- BSc, The University of Hong Kong
- PhD, Gerstner Sloan Kettering
- 646-888-3160
- Lab Phone

Assistant Attending, Breast Service
Technician

Associate Attending, Gastric & Mixed Tumor Service
Graduate Student

Graduate Student
Research Fellow

MD-PhD student
Research Technician

Research Scholar
Graduate Student
Research Fellow
Research Fellow
Graduate Student
Graduate Student

Research Fellow

Visiting Investigator
Senior Research Scientist

Research Fellow
Research Fellow
MD-PhD Student

Research Fellow

Graduate Student
Research Fellow

Scientist 3, Immunology Discovery, Genentech, San Francisco, CA








- The University of British Columbia
Lab Alumni

Postdoctoral Fellow

Postdoctoral Fellow

Postdoctoral Fellow

Research Fellow

MD/PhD Student

Research Fellow

Research Fellow

Postdoctoral Fellow

Research Scholar

MD/PhD Student

Research Associate

Research Associate

Postdoctoral Research Fellow

Postdoctoral Fellow

Postdoctoral Research Fellow
Research Technician

Research Technician

Research Technician

Research Technician

Postdoctoral Fellow

Graduate Research Assistant

Research Technician
Research Technician

Research Fellow

Graduate Student

Research Associate

Graduate Student

Research Technician

Research Fellow

Research Fellow
MD-PhD Student

Technician

Research Fellow

Junior Analyst venBio Select Advisor New York, NY

Technician

Research Associate
Research Technician

Bioinformatics Analyst
Research Fellow, Department of Surgery
Research Technician

Technician

Research Fellow
Lab Affiliations
Achievements
- Investigator, Howard Hughes Medical Institute
- Vilcek Prize in Biomedical Science, New York, NY (2018)
- Crafoord Prize, the Royal Swedish Academy of Sciences, Stockholm Sweden (2017)
- Member, National Academy of Medicine (2015)
- Member, American Academy of Arts and Sciences (2015)
Read more
- Coley Award in Basic Immunology, Cancer Research Institute (2015)
- Thomson Reuters Citation Laureate (2015)
- Member, National Academy of Sciences (2012)
- Merit Award, National Institutes of Health (2009)
- Investigator Award, American Association of Immunologists/PharMingen (1999)
- Searle Scholar Award (1993)
- Investigator, Howard Hughes Medical Institute (1993)
- Elucidation of the function of transcription factor Foxp3 in regulatory T cells and their critical role in immune homeostasis (2003-2010)
- Identification of the primary structure of MHC class II bound peptides (1991)
Get in Touch
-
Lab Head Email
-
Office Phone
-
Office Fax
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Alexander Rudensky discloses the following relationships and financial interests:
-
BioInvent International AB
Professional Services and Activities -
RAPT Therapeutics
Equity; Professional Services and Activities -
Santa Ana Bio, Inc.
Equity; Professional Services and Activities -
Sonoma Biotherapeutics, Inc.
Equity; Professional Services and Activities
-
Surface Oncology
Equity; Professional Services and Activities -
Takeda Pharmaceuticals
Intellectual Property Rights -
Vedanta
Equity; Professional Services and Activities
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].