Selected Publications: Here
Complete Publications: Here

Full list of publications also available on: Google Scholar

51. Nam, K.H. and Ordureau, A. (2024) How does the neuronal proteostasis network react to cellular cues? Biochem. Soc. Trans. 2024 Mar 15:BST20230316.

48. Paul, S., Sarraf, S.A., Nam, K.H., Zavar, L., DeFoor, N., Biswas, S.R., Fritsch, L.E., Yaron, T.M., Johnson, J.L., Huntsman, E.M., Cantley, L.C., Ordureau, A., Pickrell, A.M. (2024) NAK-associated protein 1/NAP1 activates TBK1 to ensure accurate mitosis and cytokinesis. J Cell Biol. 223(2):e202303082.

42. Nam, KH., Ordureau, A. Quantitative proteome remodeling characterization of two human reference pluripotent stem cell lines during neurogenesis and cardiomyogenesis. Proteomics. 2022 Oct;22(19-20):e2100246

39. Antico, O.*, Ordureau, A.*, Stevens, M., Singh, F., Nirujogi, R.S., Gierlinski, M., Barini, E., Rickwood, M.L., Prescott, A., Toth, R., Ganley, I.G., Harper, J.W., Muqit, M.M.K. (2021) Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1. Science Advances. 7(46):eabj0722. 

38. Ordureau, A.†, Kraus, F., Zhang, J., An, H., Park, S., Ahfeldt, T., Paulo, J.A., Harper, J.W.†. (2021) Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy. Molecular Cell. 81(24):5082-5098.e11.

37. Ordureau, A., Yu, Q., Bomgarden., R.D., Rogers, J.C., Harper, J.W., Gygi, S.P., Paulo, J.A. (2021) Super Heavy TMTpro Labeling Reagent: An Alternative and Higher-Charge-State-Amenable Stable-Isotope-Labeled TMTpro Variant. J Proteome Res. 7;20(5):3009-3013.

34. Sinha, N.K.*, Ordureau, A.*, Best, K.M.*, Saba, J.A., Zinshteyn, B., Sundaramoorthy, 34. E., Fulzele, A., Garshott, D.M., Denk, T., Thoms, M., Paulo, J.A., Harper, J.W., Bennett, E.J., Beckmann, R., Green, R. (2020) EDF1 coordinates cellular responses to ribosome collisions. eLife 9, e58828.

33. An, H.*, Ordureau, A.*, Korner, M., Paulo, J.A., Harper, J.W. (2020) Systematic Quantitative Analysis of Ribosome Inventory During Nutrient Stress. Nature 583(7815), 303-309.

31. Ordureau, A., Paulo, J.A., Zhang, J., An, H., Swatek, K.N., Cannon, J.R., Wan, Q., Komander, D., Harper J.W. (2020) Global landscape and dynamics of Parkin and USP30-dependent ubiquitylomes in iNeurons during mitophagic signaling. Molecular Cell. 77(5):1124-1142.

26. An, H., Ordureau, A., Paulo, J.A., Shoemaker, C.J., Denic, V., Harper, J.W. (2019) TEX264 is an ER-resident ATG8-interacting protein critical for endoplasmic reticulum remodeling during nutrient stress. Molecular Cell. 74(5):891-908.

24. Ordureau, A., Paulo, J.A., Zhang, W., Ahfeldt, T., Zhang, J., Cohn, E.F., Hou, Z., Heo, 24. J.M., Rubin, L.L., Sidhu, S.S., Gygi, S.P., Harper, J.W. (2018) Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics. Molecular Cell. 70(2) 211-227.

23. Harper, J.W., Ordureau, A., Heo, J.M. (2018) Building and decoding ubiquitin chains for mitophagy. Nat Rev Mol Cell Biol. 19(2):93-108.

16. Heo, J.H., Ordureau, A., Paulo, J.A., Rinehart, J., and Harper, J.W. (2015) The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy. Molecular Cell 60, 7–20.

13. Ordureau, A., Munch, C., and Harper, J.W. (2015). Quantifying ubiquitin signaling. Molecular Cell 58, 660-676.

12. Ordureau, A., Heo, J.M., Duda, D.M., Paulo, J.A., Olszewski, J.L., Yanishevski, D., Rinehart, J., Schulman, B.A., and Harper, J.W. (2015). Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy. Proc Natl Acad Sci USA 112, 6637-6642.

9. Ordureau, A., Sarraf, S.A., Duda, D.M., Heo, J.M., Jedrychowski, M.P., Sviderskiy, V.O., Olszewski, J.L., Koerber, J.T., Xie, T., Beausoleil, S.A., Wells, J.A., Gygi, S.P., Schulman, B.A., and Harper, J.W. (2014). Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis. Molecular Cell 56, 360-375.

7. Emmerich, C.H., Ordureau, A., Strickson, S., Arthur, J.S., Pedrioli, P.G., Komander, D., and Cohen, P. (2013). Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains. Proc Natl Acad Sci USA 110, 15247-15252.

6. Ordureau, A., Enesa, K., Nanda, S., Le Francois, B., Peggie, M., Prescott, A., Albert, P.R., and Cohen, P. (2013). DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA. J Biol Chem 288, 24569-24580.

5. Enesa, K., Ordureau, A., Smith, H., Barford, D., Cheung, P.C., Patterson-Kane, J., Arthur, J.S., and Cohen, P. (2012). Pellino1 is required for interferon production by viral double-stranded RNA. J Biol Chem 287, 34825-34835.

4. Gleason, C.E., Ordureau, A., Gourlay, R., Arthur, J.S., and Cohen, P. (2011). Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon beta. J Biol Chem 286, 35663-35674.

1. Ordureau, A.*, Smith, H.*, Windheim, M., Peggie, M., Carrick, E., Morrice, N., and Cohen, P. (2008). The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1. Biochem J. 409, 43-52.