We investigate how leukocytes are rapidly targeted to sites of “danger” in intact tissues, i.e. how they detect wounds or sites of infection. Misregulation of this process may lead to hyper-inflammatory disease. Chronic inflammatory states, in turn, promote cancer. Although the complex cytokine networks that govern amplification and resolution of inflammatory responses have been intensely studied, the initial mechanisms that regulate leukocyte targeting in tissues remain very little understood.
Philipp Niethammer, PhD
Research FocusCell biologist Philipp Niethammer investigates tissue damage responses with advanced imaging approaches in zebrafish.
EducationPhD, European Molecular Biology Laboratories & Hamburg University, Germany
- Jelcic M, Enyedi B, Xavier JB, Niethammer P. Image-Based Measurement of H2O2 Reaction-Diffusion in Wounded Zebrafish Larvae. Biophys J. 2017 May 9;112(9):2011–2018. PMCID: PMC5425381
- Enyedi B, Niethammer P. Nuclear membrane stretch and its role in mechanotransduction. Nucleus. 2017 Mar 4;8(2):156–161. PMCID: PMC5403133
- European Molecular Biology Organization Long Term Fellow (2006)
- Human Frontiers Science Program Long Term Fellow (2007)
- Dorsett L. Spurgeon Distinguished Research Award (2009)
- Louis Gerstner Young Investigator (2012)
- American Asthma Foundation Scholar (2014)