Mark J. Jelcic, PhD

Scientist at Fate Therapeutics Inc, San Diego, CA

Mark J. Jelcic, PhD

Scientist at Fate Therapeutics Inc, San Diego, CA

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Mark J. Jelcic

Dissertation

Uncovering ATP Interactors and Signaling Mechanisms in Inflammation and Wound (2020)

Start Year

2013

End Year

2020

Education

BA, New York University

Mark studies the mechanisms of nucleotide mediated wound repair.

Fellowships

Olayan Fellowship (2014-2015)

Publications

Shen Z, Belcheva KT, Jelcic M, Hui KL, Katikaneni A, Niethammer P. (2022) A synergy between mechanosensitive calcium- and membrane-binding mediates tension-sensing by C2-like domains. Pro Natl Acad Sci U S A.

Jelcic M, Wang K, Hui KL, Cai XC, Enyedi B, Luo M, Niethammer P.(2020) A Photoclickable ATP-Mimetic Reveals Nucleaotide Interactors in the Membrane Proteome. Cell Chem Biol. PMID: 32521230 [Epub ahead of print]

Katikaneni A, Jelcic M, Gerlach GF, Ma Y, Overholtzer M, Niethammer P. (2020) Lipid peroxidation regulates long-range wound detection through 5-lipoxygenase in zebrafish. Nat Cell Biol. [Epub ahead of print]

Jelcic M, Enyedi B, Niethammer P. (2019) Quantitative Imaging of Endogenous and Exogenous H2O2 Gradients in Live Zebrafish Larvae. Methods Mol Biol. 1982 , 283-299.

Jelcic M, Enyedi B, Xavier JB, Niethammer P. (2017) Image-Based Measurement of H2O2 Reaction-Diffusion in Wounded Zebrafish Larvae. Biophys J. 112, 2011-2018. PMCID: PMC5425381 [Available on 2018-05-09]

Malonis RJ, Fu W, Jelcic MJ, Thompson M, Canter BS, Tsikitis M, Esteva FJ, Sánchez I. (2017) RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling. J Biol Chem. 292, 7435-7451. PMCID: PMC5418044 [Available on 2018-05-05]

Enyedi B, Jelcic M, Niethammer P. (2016) The Cell Nucleus Serves as a Mechanotransducer of Tissue Damage-Induced Inflammation. Cell 165, 1160-70. PMCID: PMC4875569 [Available on 2017-05-19]

Jelcic M, Niethammer P. (2015) Do not scratch that mole! Trends Immunol36, 503-504.