The Michael Kharas Lab

The Michael Kharas Lab

The Kharas lab is working to identify critical pathways in both normal and leukemic hematopoietic cells.

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Pictured: Michael Kharas

Michael G Kharas, PhD

Assistant Professor

Research Focus

Cancer biologist Michael Kharas studies RNA regulators of self-renewal in both normal and leukemic hematopoiesis.

Education

PhD, University of California Irvine

Publications

  • Ly P Vu, Brian F Pickering, Yuanming Cheng , Sara Zaccara, Diu Nguyen, Gerard Minuesa, Timothy Chou, Arthur Chow, Yogesh Saletore, Matthew MacKay, Jessica Schulman, Christopher Famulare, Minal Patel, Virginia M Klimek, Francine E Garrett-Bakelman, Ari Melnick, Martin Carroll, Christopher E Mason, Samie R Jaffrey & Michael G Kharas The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nature Medicine. 2017 September 18. doi:10.1038/nm.4416.
  • Kotini AG, Chang CJ, Chow A, Yuan H, Ho TC, Wang T, Vora S, Husser C, Olszewska M, Alexander S, Perumal D, Teruya-Feldstein J, Klimek VM, Spyridonidis A, Rampal R, Silverman L, Reddy EP, Papaemmanuil, E, Parekh S, Greenbaum B, Leslie C, Kharas MG*, Papapetrou EP*. Stage-specific induced pluripotent stem cells delineate a roadmap to myeloid transformation. Cell Stem Cell. 2017 Mar 2; 20:1-14 PMID: 28215825
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Selected Achievements

  • Leukemia and Lymphoma Society Career Development Award (2017)
  • Alex Lemonade Stand Foundation ‘A’ Award (2016)
  • American Society of Hematology Junior Faculty Scholar Award (2011)
  • Kimmel Scholar Award (2013)
  • V-Scholar Award (2013)