Joseph N. Pucella, PhD

Graduate Student

Joseph N. Pucella, PhD

Graduate Student

Joseph N. Pucella

Lab Phone



The Elusive Role of MIR-182 and Clustered Paralogs in Adaptive Immunity

Start Year


End Year



Cornell University


Olayan Fellowship (2011-2012)


Yen WF, Sharma R, Cols M, Lau CM, Chaudhry A, Chowdhury P, Yewdell WT, Vaidyanathan B, Sun A, Coffre M, Pucella JN, Chen CC, Jasin M, Sun JC, Rudensky AY, Koralov SB, Chaudhuri J. (2019) Distinct Requirements of CHD4 during B Cell Development and Antibody Response. Cell Rep. 27, 1472-1486.

Pucella JN, Cols M, Yen WF, Xu S, Chaudhuri J. (2019) The B Cell Activation-Induced miR-183 Cluster Plays a Minimal Role in Canonical Primary Humoral Responses. J Immunol. pii: ji1800071.

Pucella JN, Chaudhuri J. (2017) AID Invited to the G4 Summit. Mol Cell67, 355-357.

Yen WF, Chaudhry A, Vaidyanathan B, Yewdell WT, Pucella JN, Sharma R, Liang Y, Li K, Rudensky AY, Chaudhuri J. (2017) BRCT-domain protein BRIT1 influences class switch recombination. Proc Natl Acad Sci U S A pii: 201708211 [Epub ahead of print]. PMCID: PMC5547652 [Available on 2018-02-01]

Pucella JN, Yen WF, Kim MV, van der Veeken J, Socci ND, Naito Y, Li MO, Iwai N, Chaudhuri J. (2015)  miR-182 Is Largely Dispensable for Adaptive Immunity: Lack of Correlation between Expression and Function. J Immunol., 195, 1903.

Vaidyanathan B., Yen, W., Pucella, J.,and Chaudhuri, J. (2014)  AIDing Chromatin and  Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination.  Front Immunol5, 1-13. PMID: 24734031; PMCID: PMC3975107.

Vuong, B., Herrick-Reynolds, K., Vaidyanathan, B., Pucella, J., Ucher, A., Donghia, N., Gu, X., Nicolas, L., Nowak, U., Rahman, N., Strout, M., Mills, K., Stavnezer, J., and Chaudhuri, J. (2013) A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination. Nat Immunol14, 1183-1189. PMID: 24097111; PMCID: PMC4005274.