Immunology Program

The Jayanta Chaudhuri Lab

Jayanta Chaudhuri, PhD

Professor

Laboratory of Molecular and Cellular Immunology

Recombination, genomic integrity, and heterogeneity in B cells

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Featured News

At Work: Immunologist Jayanta Chaudhuri

Immunologist Jayanta Chaudhuri has long been interested in biology, Mendelian genetics, and the story of how life evolved.

In the Community

Allysia Matthews, with Citymeals-on-Wheels staff donating reusable ice packs

Giving Supplies a Second Life, and Making an Environmental Impact in the Process

Tuesday, July 8, 2014

Memorial Sloan Kettering “green” committees focus on waste reduction and energy efficiency throughout the institution while donating useful supplies to New York–area nonprofits.

In the Lab

Pictured: Charles L. Sawyers, William Polkinghorn & Simon Powell

Molecular Studies Explain Effectiveness of Longtime Treatment for Prostate Cancer

Thursday, December 12, 2013

Laboratory studies have revealed an explanation for why androgen-deprivation therapy makes radiation therapy more effective in the treatment of high-risk prostate cancer.

Publications

William T. Yewdell, Youngjun Kim, Priyanka Chowdhury, Colleen M. Lau¹, Ryan M. Smolkin, Kalina T. Belcheva, Keith C. Fernandez, Montserrat Cols, Wei-Feng Yen, Bharat Vaidyanathan, Davide Angeletti, Adrian B. McDermott, Jonathan W. Yewdell, Joseph C. Sun, Jayanta Chaudhuri. (2020) A hyper-IgM syndrome mutation in AID disrupts G-quadruplex binding and chromatin localization. Immunity (In Press).

Angeletti, D., I. Kosik, J. J. S. Santos, W. T. Yewdell, C. M. Boudreau, V. V. A. Mallajosyula, M. C. Mankowski, M. Chambers, M. Prabhakaran, H. D. Hickman, A. B. McDermott, G. Alter, J. Chaudhuri, and J. W. Yewdell. (2019) Outflanking immunodominance to target subdominant broadly neutralizing epitopes. Proc Natl Acad Sci USA 116: 13474-13479. PMCID: PMC6986270

Pucella JN, Cols M, Yen W-F, Xu S and Chaudhuri J. The B cell activation induced miR-183 cluster plays a minimal role in canonical primary humoral responses. (2019) J. Immunology; 202(5): 1383-1396. PMCID: PMC6986270

Nicolas L, Cols M, Smolkin R, Fernandez KC, Yewdell WT, Yen W-F, Zha S, Vuong B and Chaudhuri J. ATM influences germinal center integrity.(2019) Cutting Edge: Journal of Immunology; 202 (11): 3137-3142. PMCID: PMC6529280

Yen W-F, Sharma R, Cols M, Lau CM, Chaudhry A, Chowdhury P, Yewdell WT, Vaidyanathan B, Sun A, Coffre M, Pucella JN, Chen C-C, Jasin M, Sun JC, Rudensky AY, Koralob SB and Chaudhuri J. (2019). Distinct requirements of CHD4 during B cell development and antibody response. Cell Reports 27(5):1472-1486. PMCID: PMC6527137

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People

Jayanta Chaudhuri, PhD

Professor

Immunologist Jayanta Chaudhuri studies the mechanisms of immunoglobulin gene diversification.
PhD, Albert Einstein College of Medicine

[email protected]: Email Address
646-888-2357: Office Phone

Members

Jayanta Chaudhuri, PhD — Jayanta Chaudhuri
Lab Head

Veronica Shields
Administrative Assistant

Lab Alumni

Laura Nicolas, PhD — Laura Nicolas
Postdoctoral Research Fellow

Kayleigh-Herrick Reynolds
Research Technician

William Terry

Clinical Fellow n Pediatrics

Bao Q. Vuong

Postdoctoral Research Fellow

Wei-Feng Yen
Postdoctoral Research Fellow

Lab Affiliations

Open Positions

To learn more about available postdoctoral opportunities, please visit our Career Center

Get in Touch

[email protected]

Lab Head Email
646-888-2357

Office Phone
646-422-0495

Office Fax
646-888-2334/2344

Lab Phone

Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Jayanta Chaudhuri discloses the following relationships and financial interests:

No disclosures meeting criteria for time period

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].

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