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The Jayanta Chaudhuri Lab: Publications

Visit PubMed for a full listing of Jayanta Chaudhuri’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Zheng S, Vuong BQ, Vaidyanathan B, Lin J-Y, Huang F-T and Chaudhuri J. Non-coding RNA generated following lariat debranching mediates targeting of AID to DNA. Cell 2015 (In Press).

Pucella JN, Yen-W-F, Kim MJ, van der Veeken J, Socci ND, Naito Y, Li MO, Iwai N and Chaudhuri J. mIR-182 is largely dispensable for adaptive immunity: lack of correlation between expression and function. Journal of Immunology 2015 (In Press).

Matthews A, Husain S, and Chaudhuri J. Binding of AID to DNA does not correlate with mutator activity. Journal of Immunology 2014; 193:252-57.

Matthews A, Zheng S, Dimenna L, and Chaudhuri J. Class switch recombination: Choreography of non-coding transcription, targeted DNA deamination and long-range DNA repair. Advances in Immunology  2014; 122:1-57.

Vaidyanathan B, Yen WF, Pucella, JN and Chaudhuri J. AIDing chromatin and transcription-coupled orchestration of immunoglobulin class switch recombination. Frontiers in Immunology 2014; 5:1-13.

Vuong BQ, Herrick-Reynolds K, Vaidyanathan B, Pucella J, Ucher AJ, Donghia N, Gu X, Nicolas L, Nowak U, Rahman N, Strout MP, Mills KD, Stavnezer J and Chaudhuri J. A novel DNA break and phosphorylation-dependent positive feedback promotes class switch recombination. Nat Immunol. 2013; 14: 1183-89

Polkinghorn WR, Parker JS, Lee MX, Kass EM, Spratt DE, Iaquinta PJ, Arora VK, Yen WF, Cai L, Zheng D, Carver BS, Chen Y, Watson PA, Shah NP, Fujisawa S, Goglia AG, Gopalan A, Hieronymus H, Wongvipat J, Scardino PT, Zelefsky MJ, Jasin M, Chaudhuri J, Powell SN, Sawyers CL. Androgen receptor signaling regulates DNA repair in prostrate cancers. Cancer Discovery. 2013. 3: 1245-53.

Nicolas L and Chaudhuri J. 4C-ing the IgH landscape. Immunity. 2013; 39:199-201.

Kumar R,DiMenna L, Schrode N, Liu T-C, Franck P, Munoz-Descalzo S, Hadjantonakis A, Chaudhuri J, Elemento O, and Evans T. AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes. Nature 2013; 500:89-92.

Vuong BQ and Chaudhuri J. Understanding and Controlling ADD - AID-dependent Deamination and DNA Damage. Seminars in Immunology. 2012; 24:264-272.

Nowak U, Matthews A, Zheng S and Chaudhuri J. The splicing regulator PTBP2 is an AID interacting protein and promotes binding of AID to switch region DNA. Nat Immunol. 2011 Feb;12(2):160-6. Epub 2010 Dec 26.

Lee-Theilen M, Matthews AJ, Kelly D, Zheng S and Chaudhuri J. CtIP promotes microhomology-mediated end-joining during class switch recombination. Nat Struct Mol Biol. 2011 Jan;18(1):75-9. Epub 2010 Dec 5.

Lee-Theilen M and Chaudhuri J. (2010) Walking the AID tightrope. Nat Immunol. 11: 107-109.

Vuong BQ, Lee M, Kabir S, Irima C, Macciarulo G, McKnight GS and Chaudhuri J. (2009) Specific recruitment of PKA to the immunoglobulin locus regulates class switch recombination. Nature Immunology, 10:420-426.

Cheng HL+, Vuong BQ+, Basu UB+, Franklin F, Schwer B, Astarira J, Phan RT, Datta A, Manis J, Alt FW and Chaudhuri J. (2009) Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice. Proc. Natl. Acad. Sci. 106:2717-2722. (+equal contribution)

Chaudhuri J, Basu U, Zrrin A, Yan C, Franco S, Perlot T, Vuong B, Wang J, Phan RT, Datta A, Manis J and Alt FW. (2007). Evolution of immunoglobulin heavy chain class switch recombination mechanism. Advances in Immunology, 94:157-214.

Basu U+, Chaudhuri J+,, Alpert C, Dutt S, Ranganath S, Li G, Schrum JP, Manis JP, Alt FW. (2005) The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation. Nature. 438(7067):508-11. (+ equal contributions)

Chaudhuri J, Khuong C, and Alt FW. (2004) Replication Protein A interacts with AID to promote deamination of somatic hypermutation targets. Nature, 430: 992-998.

Chaudhuri J, Tian M, Khuong C, Pinaud E, Alt FW. (2003) Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature, 422:726-730.

Chaudhuri J and Alt FW. (2004) Class Switch Recombination: Interplay of transcription, DNA deamination and DNA repair. Nature Reviews Immunology. 4: 541-52

Zarrin AA, Alt FW, Chaudhuri J, Stokes N, Kaushal D, Du Pasquier L and Tian M. (2005) An evolutionarily conserved target motif for immunoglobulin class-switch recombination. Nat Immunol, 5:1275-1281.

Dudley DD, Chaudhuri J, Bassing CH, Alt FW (2005) Mechanism and Control of V(D)J Recombination versus Class Switch Recombination: Similarities and Differences. Adv Immunol, 86: 43-112.

Rooney S, Chaudhuri J, and Alt FW. (2004) The role of the non-homologous end-joining pathway in lymphocyte development. Immunological Reviews. 200: 115-131.

Dedeoglu F, Horwitz B, Chaudhuri J, Alt FW, Geha RS. (2004) Induction of AID gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkB. Int. Immunol. 16: 395-404.

Gao Y, Chaudhuri J, Zhu C, Davidson L, Weaver DT, Alt FW. (1998) A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination. Immunity. 9:367-76.