The lab is seeking a highly motivated and team oriented post-doctoral researcher to conduct molecular and biochemical experiments to allow functional characterization of novel candidate genes identified through next generation sequencing and assess their role in cancer susceptibility. Applicants with a curious mindset and interest in technology/assay development are especially encouraged to apply. We are looking for a molecular biologist, preferably with a background in germline genetics and cancer biology. The goal is to merge clinical, genotypic and molecular studies to dissect complex phenotypes seen in cancers. MSKCC provides an interactive setting with opportunities for collaboration with other independent research groups.
Current projects of interest focus on the role of DNA repair gene mutations in cancer susceptibility. The applicant should have a strong interest and ideally prior experience with DNA repair pathways and relevant biochemical assays. An interest in the development of new tools to interrogate genetic variants on a larger scale would be ideal.
The successful applicant should have:
- A PhD degree in molecular biology/cancer biology/biochemistry
- Essential wet lab skills such as cell culture, molecular cloning, DNA, RNA and protein isolation, Western blotting, immunostaining etc
- Extensive experience with cell culture/ in vitro assays is required, additional familiarity with animal models is an advantage
Additional desirable skills include:
- Prior experience with CRISPR/Cas9 or other genome editing techniques
- Familiarity with next generation sequencing approaches
- Experience in developing/carrying out high throughput assays
- Familiarity with genetic datasets
Appointment will be on an annual basis, with a starting salary as per NIH guidelines, based on qualification and prior experience. We hope to hire in the next 45 days. Generic applications are not encouraged.