Postdoctoral Fellow in Cancer Biology and Genetics

Postdoctoral Fellow in Cancer Biology and Genetics


The Clinical Cancer Genetics Research Lab (CGRL) focuses on the discovery and functional characterization of inherited genetic variations that influence the risk of cancer. The lab has a track record in discovery of germline mutations in cancer and novel loci using genome-wide association studies and studying their effect through in vitro modeling. The lab is currently utilizing large-scale next generation sequencing and functional assays to understand the role of rare variants that are predicted to have physiological impact in human cancers. Recent publications include PMID: 27655433, PMID:26102509, PMID: 27433846, PMID: 24013638 and PMID:28873162. See also our lab website at:

The lab is seeking a highly motivated and team oriented post-doctoral researcher to conduct molecular and biochemical experiments to allow functional characterization of novel candidate genes identified through next generation sequencing and assess their role in cancer susceptibility. Applicants with a curious mindset and interest in technology/assay development are especially encouraged to apply. We are looking for a molecular biologist, preferably with a background in germline genetics and cancer biology. The goal is to merge clinical, genotypic and molecular studies to dissect complex phenotypes seen in cancers. MSKCC provides an interactive setting with opportunities for collaboration with other independent research groups. 

The successful applicant should have: 

  • A PhD degree in molecular biology/cancer biology/biochemistry
  • Essential wet lab skills such as cell culture, molecular cloning, DNA, RNA and protein isolation, Western blotting, immunostaining etc
  • Extensive experience with cell culture/ in vitro assays is required, additional familiarity with animal models is an advantage

Additional desirable skills include:

  • Prior experience with CRISPR/Cas9 or other genome editing techniques
  • Familiarity with next generation sequencing approaches
  • Experience in developing/carrying out high throughput assays 
  • Familiarity with genetic datasets 

Appointment will be on an annual basis, with a starting salary as per NIH guidelines, based on qualification and prior experience. We hope to hire in the next 45 days. Generic applications are not encouraged.

Application Requirements

Informal inquiries are welcome and can be made to Dr. Sabine Topka ( Please note – this address is for enquiries only and CVs must be submitted in line with the instructions below.

Please send CV, a letter outlining your interest and names/contact information of three references via email to:

Please use the following format for the subject line: Postdoc 2018-02 <Applicant Name>
MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.  
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