Developmental Biology Program

The Eric Lai Lab

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Research

Eric C. Lai, PhD
Eric C. Lai, PhD


Professor

As a laboratory of developmental biology, our guiding interest is to comprehend how complex biological patterns can be assembled with stereotyped precision. This requires a detailed understanding of how cells come to execute appropriate behaviors — be it adoption of specific cell fates, proliferation, or apoptosis — and do so at the right times, in the right places, and in the right numbers. Dysfunction of processes that direct normal tissue patterning results not only in developmental disorder but also underlies adult disease. Tellingly, many factors whose mutation is relevant to human cancer were first identified and characterized with respect to development in model organisms. To study these topics, we utilize integrative approaches, combining genetics, biochemistry, and genomewide approaches, to elucidate detailed molecular mechanisms and use these to understand in vivo biology as well as decipher genomic regulatory networks.

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Research Projects

The Eric Lai Lab

Publications

People

Eric C. Lai, PhD

Eric C. Lai, PhD



Professor

  • The Lai laboratory integrates genetics, biochemistry, and genomewide approaches to study diverse regulatory networks during patterning and behavior.
  • BA, Harvard College
  • PhD, University of California, San Diego
laie@mskcc.org
Email Address
212-639-5578
Office Phone
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Members

Daniel Lopez Garaulet
Daniel Lopez Garaulet

Research Associate

David Jee
David Jee

Graduate Student

Pictured: Brian J. Joseph
Brian J. Joseph

Graduate Student

Lijuan Kan
Lijuan Kan

Research Fellow

Chun-Ming Lai
Chun-Ming Lai

Research Scholar

Gillian Ching-Jung Lin
Gillian Ching-Jung Lin

Graduate Student

Albertomaria Moro
Albertomaria Moro

Research Associate

Ashley  Ramos
Ashley Ramos

Administrative Assistant I

Silvia Rodriguez
Silvia Rodriguez

Fly Facility Aide, Lead

Chaz Scala
Chaz Scala

Research Technician

Renfu  Shang
Renfu Shang

Research Fellow

Eun sil Park
Eun sil Park

Research Scholar

Jeffrey Vendanayagam
Jeffrey Vendanayagam

Research Fellow

Lu  Wei
Lu Wei

Research Fellow

Yang Yu
Yang Yu

Research Fellow

Binglong Zhang
Binglong Zhang

Research Fellow

Lab Alumni
Anthony Guerrero

Research Technician

Sonali Majumdar
Sonali Majumdar

Research Scholar

Bidisha Roy
Bidisha Roy

Research Fellow

Piero Sanfilippo, BA
Piero Sanfilippo

Graduate Student

Yu-ting Chou

Research Technician

Joshua Hagen

MD-PhD Student

Hong Duan

Senior Research Scientist

Peter Smibert

Research Fellow

Jr-Shiuan Yang

Graduate Student

Kailiang Sun
Michael Phillips
Fernando Bejarano
Zhigang Jin
Nicolas Robine
Qi Dai
Alex Flynt

Research Fellow

Katsutomo Okamura

Research Fellow

Jacqueline Sanchez-Shabazz

Administrative Assistant

Lab Affilations

Achievements

  • Louise and Allston Boyer Young Investigator Award for Basic Research, Memorial Sloan Kettering Cancer Center (2009)
  • Kimmel Scholar, Sidney Kimmel Foundation for Cancer Research (2007-2009)
  • V Scholar, V Foundation for Cancer Research (2006-2008)
  • Career Award in the Biomedical Sciences, Burroughs Wellcome Fund (2005)
  • Special Fellow, Leukemia and Lymphoma Society (2004-2006)
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  • Fellow, Damon Runyon Cancer Research Foundation (2000-2003)
  • First elucidation of the major basis of miRNA-target recognition
  • Discovery of novel transcription and signaling and factors that regulate neural development

Open Positions

Career Opportunities

The Lai lab is currently recruiting for postdoctoral fellows and research technicians.

Apply now

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Eric C. Lai discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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