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In the Lab
MSK Scientists Build "Armored" CAR T Cells to Smite Solid Tumors
The engineered immune cells secrete powerful drugs as a layer of defense.
In the Lab
This image shows cancer cells (white) and pericytes (green) clinging to capillaries (red). The blue dots are nuclei.
Scientists Identify Growth Signal for Metastatic Cancer "Seeds"
Targeting this signal with drugs might be one way to stop cancers from spreading.
Feature
NK cells attacking
Meet the Unsung Immune Cell that Could Change Immunotherapy
A lesser-known immune cell is suddenly getting more attention in the field of cancer immunology.
Finding
A doctor examines a mole.
Don't Scratch That Mole? Scientists Are Learning More about Inflammation and Cancer
It's not only what's inside your cells that determines your cancer risk. It's what surrounds them too.
Feature
Omar Abdel-Wahab
What Is Epigenetics, and Why Is Everyone Talking about It?
The word “epigenetic” literally means “above the genes.” Calico cats demonstrate a type of epigenetic inheritance called X-inactivation.
Finding
Large cells filled with yellow-colored fat
Cancer Cells Eat Fat to Grow and Spread
Research conducted in zebrafish shows that melanoma cells have an affinity for fat, and that eating it makes them more aggressive.
Finding
Scanning electron micrograph (SEM) of T lymphocyte cells (blue) attached to a red cancer cell.
Discovery of Unusual Cell Type Could Help Guide Immunotherapy
A newly identified group of immunosuppressive cells could provide insight into the effects of immunotherapy drugs.
In the Lab
Blue cells containing small red and green dots on a black background
Scientists Pinpoint a New Cause of Resistance to EGFR-Targeting Drugs
Multiple copies of a gene called <em>YES1</em> appear to be responsible for certain precision drugs losing their effectiveness.
In Brief
MSK light bright image
Can You Hear Me Now? Scientists Find Nanoparticles Have a Language of Their Own
Nanoparticles were thought of a silent partner in imaging technologies. They’re now being recognized as an important source of subatomic chatter.
In the Lab
abstract red and blue lines suggestive of metabolic pathways
Scientists Create First-of-Its-Kind Metabolic Road Map of Cancer
The online resource will serve as a benchmark for researchers studying metabolism and cancer.