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Alban Ordureau explores molecular signaling pathways that regulate cellular homeostasis, with a focus on the ubiquitin and autophagy systems.
The Antonsecu lab focuses on translocation-associated sarcoma pathogenesis and generating in vitro models.
The Lareau Lab synthesizes computational and experimental genomics methods to study how immune cells in our bodies adapt, expand, differentiate, and evolve over an individual’s lifetime.
Developmental biologist Luis F. Parada uses genetically engineered mouse models to study neurofibromatosis, brain tumors, cancer stem cells, and tumor progression.
The Gladkova lab studies the mechanisms and signals that reshape cellular organelle architecture in response to physiological stimuli.
Cancer Immunologist Andrea Schietinger investigates immune responses to cancer, molecular mechanisms underlying tumor-induced T cell dysfunction, and new approaches for cancer immunotherapy.
Xinbo Yang’s lab applies structural biology and protein engineering to decode T cell receptor specificity in cancer and autoimmune disease.
The Lito lab investigates the properties of oncoproteins that drive cancer cell growth, with a focus on cancers driven by RAS mutations.
The Chiosis lab uses a unique chemical biology approach to understand, diagnose, and treat cellular processes associated with chronic molecular stress, with the ultimate goal of developing novel therapeutic options for use in the clinic.
Immunologist Joseph Sun investigates the natural killer cell response against infection and cancer.