The laboratory investigates programmed cell death, a cellular process functioning to maintain tissue homeostasis and eliminate damaged or unwanted cells in multicellular organism. Programmed cell death plays crucial roles in development, immune responses, and many other physiological events. Malfunction of programmed cell death can lead to diseases such as cancer, immune disorders, and neurodegenerative diseases. We employ multiple approaches to study the molecular basis of programmed cell death. We also seek to translate our basic research findings into novel cancer therapies.
Xuejun Jiang, PhD
Research FocusCell biologist Xuejun Jiang studies programmed cell death, molecular mechanisms, and their roles in tumorigenesis.
EducationPhD, University of Texas Southwestern Medical Center at Dallas
- Gao M, Monian P, Quadri N, Ramasamy R, Jiang X. Mol Cell. Glutaminolysis and Transferrin Regulate Ferroptosis. 2015 Jul 16;59(2):298-308. doi: 10.1016/j.molcel.2015.06.011. Epub 2015 Jul 9.
- Wong PM, Feng Y, Wang J, Shi R, Jiang X.Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. Nat Commun. 2015 Aug 27;6:8048. doi: 10.1038/ncomms9048.
- Louis and Allston Boyer Young Investigator Award for Basic Research, Memorial Sloan Kettering Cancer Center (2007)
- Scholar, American Cancer Society (2007-2010)
- Catherine and Frederick Adler Chair for junior faculty, Memorial Sloan Kettering Cancer Center (2006)
- V Scholar, The V Foundation for Cancer Research (2004-2006 )
- Alfred Bressler Scholar, Alref W. Bresller Scholars Fund (2004-2007)
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- Sigma Xi Award, UT Southwestern (1998)
- Robert A. Welch Predoctoral Fellowship, UT Southwestern (1995-1999)