Cancer Biology & Genetics Program

The Viviane Tabar Lab

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Research

Pictured: Viviane Tabar
Viviane Tabar, MD


Professor

I am a neurosurgeon-scientist and Chair of the Department of Neurosurgery. I have clinical expertise in the surgical management of brain tumors such as complex gliomas, meningiomas, and skull base tumors.

The lab is focused on two major themes: harnessing the potential of human pluripotent stem cells for brain repair and tumor modeling and studying glioma biology with a focus on tumor cell heterogeneity and the microenvironment.

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Research Projects

Tabar Lab

Featured News

Lorenz Studer and Viviane Tabar
Upcoming Clinical Trial Will Test New Cell Therapy for Parkinson’s Disease in Humans

Study will be the first clinical trial testing an investigational stem cell therapy aimed at restoring lost brain cells called neurons in people with advanced Parkinson’s disease (PD).
In the Lab
Fibrous extensions of a nerve cell (red) and an oligodendrocyte (green) growing on top of the nerve cell
Can Stem Cells Be Taught to Repair a Radiation-Damaged Brain?

In a recent study, Memorial Sloan Kettering scientists used stem-cell engineering to repair brain injuries in rats. The results raise hope for future therapies that could prevent or fix nerve damage in cancer patients who need brain radiation.
In the Lab
Pictured: Viviane Tabar
Investigators Use Stem Cells to Study Rare Pediatric Brain Tumors

Investigators have created the first-ever genetically engineered model of cancer made from human embryonic stem cells in culture.

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Publications

 

Berlin C, Lange K, Lekaye HC, Hopland K, Phillips S, Piao J, Tabar V. Long-term clinically relevant rodent model of methotrexate-induced cognitive impairment. Neuro Oncol. 2020 April 2; 22(8): 1126-1137PMCID: PMC7594568.

Dincer Z, Piao J, Niu L, Ganat Y, Kriks S, Zimmer B, Shi S, Tabar V, Studer Let al. Specification of functional cranial placode derivatives from human pluripotent stem cells. Cell Rep. 2013;5(5):1387-1402.  PMCID: PMC3887225

Funato K, Major T, Lewis PW, Allis CD, Tabar V. Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation. Science. 2014 Dec 19;346(6216):1529-33. PMCID: PMC4995593

Funato K, Smith RC, Saito Y, Tabar V. Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma. Cell Stem Cell. 2021 Feb 17: S1934-5909(21)00053-9. PMCID: PMC8106629.

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People

Pictured: Viviane Tabar

Viviane Tabar, MD



Professor

  • Physician-scientist Viviane Tabar focuses on stem cells as tools for brain repair and for modeling brain cancer.
  • MD, American University of Beirut
212-639-3006
Office Phone
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Physician profile

Members

Kosuke Funato
Kosuke Funato

Senior Research Assistant

Jinghua Piao
Jinghua Piao

Senior Research Assistant

Zaki Abou Mrad

Postdoctoral Fellow

Nidia Claros

Research Lab Manager

Shkurte Ademi Donohue
Shkurte Ademi Donohue

Research Technician

Elena Goldberg
Elena Goldberg

Scientific Research Manager

Kelsey Hopland
Kelsey Hopland

Graduate Student

Lucia Ruiz Perera
Lucia Ruiz Perera

Research Fellow

Yanhong Yang
Yanhong Yang

Research Scholar

Kenny Kwok Hei Yu

Instructor, Dept. of Neurosurgery

Lab Alumni
Petrina Georgala

Research Associate

Tamara Major

Research Associate

Peter Morgenstern

Research Fellow

Ryan C. Smith
Ryan C. Smith

Scientist at BlueRock Therapeutics, New York, NY

Rong Wang, PhD
Rong Wang

Research Associate

Ran Xu

Research Fellow

Leif Droms

Research Technician

Nigel Durham

Research Technician

Vladimir P. Bermudez, PhD
Vladimir P. Bermudez

Scientific Research Manager

Monalisa Navare
Monalisa Navare

Research Technician

Gabriel Duran Rehbein, MD
Gabriel Duran Rehbein

Research Fellow

Lab Affiliations

Achievements

Open Positions

To learn more about available postdoctoral opportunities, please visit our Career Center

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Viviane Tabar discloses the following relationships and financial interests:

  • American University of Beirut
    Fiduciary Role/Position
  • BlueRock Therapeutics
    Provision of Services

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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