The Michael Overholtzer Lab

Pictured: Overholtzer Lab

My laboratory investigates mechanisms of normal to tumor cell conversion, with a focus on basic epithelial cell biology, including the process entosis that we recently described. Entosis induces cell death by driving the formation of cell-in-cell structures and may be a novel mechanism of tumor suppression.

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Pictured: Michael Overholtzer

Michael Overholtzer, PhD

Associate Professor

Research Focus

Cell biologist Michael Overholtzer studies the mechanisms of tumor initiation and progression, cell adhesion, and cell death.


PhD, Princeton University

Research Projects

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