Molecular Biology Program
The Iestyn Whitehouse Lab
The Whitehouse lab is broadly interested in understanding how basic DNA dependent transactions, such as DNA replication and gene transcription, are influenced by chromatin. We use a combination of biochemical, molecular biological and genomics approaches.
High-resolution mapping of DNA replication dynamics in S. cerevisiae. McGuffee S, Smith D, Whitehouse I. Manuscript in preparation.
Intrinsic Coupling of Lagging Strand Synthesis to Chromatin Assembly. Smith D, Whitehouse I. Nature, 2012. In press.
Chromatin remodeling around nucleosome-free regions leads to repression of noncoding RNA transcription. Yadon AN, Van de Mark D, Basom R, Delrow J, Whitehouse I, Tsukiyama T. Mol Cell Biol. 2010 Nov;30(21):5110-22. Epub 2010 Aug 30.
Iestyn Whitehouse, PhD
- Molecular biologist Iestyn Whitehouse investigates chromatin structure and the function of ATP-dependent chromatin remodelling enzymes.
- PhD, The University of Dundee
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