Our research focuses specifically on imaging of genitourinary and gynecological cancers, particularly the development and validation of biomarkers derived from cross-sectional imaging and molecular imaging techniques, including dynamic contrast-enhanced MRI, diffusion-weighted MRI, 1H-MR spectroscopy, PET/CT, MRI/PET, and hyperpolarized (HP) MRI. It also involves radiomics and radiogenomics analyses and the use of advanced computing tools, including machine learning and artificial intelligence, to enhance radiology workflow and offer streamlined approaches to lesion detection and characterization.
In the field of prostate imaging, our laboratory has established new clinical paradigms for the use of multiparametric MRI (combining anatomic, functional and/or metabolic imaging sequences) to inform the management of clinically significant disease and the assessment of patients with clinically low-risk prostate cancer being considered for, or undergoing, active surveillance. We are also engaged in the development of novel targeted molecular imaging contrast agents.
Our laboratory is furthermore dedicated to developing the careers of young investigators and supporting them on their paths to independence. Dr. Hricak works with non-profit agencies in the United States and abroad on multiple programs to train future leaders in the field of imaging sciences. These include an NIH-funded U54 CCNY-MSKCC Partnership grant, which she co-leads with Dr. Karen Hubbard, Professor of Biology at the City College of New York, to increase the numbers of competitively trained, underrepresented minority students who enroll in and complete MD, PhD, DO, and MD/PhD programs and who pursue cancer-related research careers. In addition, with the New York City Department of Education, we run a mentored research training program for juniors from New York City public high schools. We are deeply committed to training the next generation of cancer imaging scientists.