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The Danwei Huangfu Lab: Publications

Visit PubMed for a full listing of Danwei Huangfu’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Shi ZD, Lee K, Yang D, Amin S, Verma N, Li QV, Zhu Z, Soh CL, Kumar R, Evans T, Chen S, Huangfu D.. Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. Cell Stem Cell. 2017 Feb 8. pii: S1934-5909(17)30001-2. doi: 10.1016/j.stem.2017.01.001. [Epub ahead of print]

Zhu Z, Li QV, Lee K, Rosen BP, González F, Soh CL, Huangfu D. Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes. Cell Stem Cell. 2016 Jun 2;18(6):755-68. doi: 10.1016/j.stem.2016.03.015.

Wang Q, Zou Y, Nowotschin S, Kim SY, Li QV, Soh CL, Su J, Zhang C, Shu W, Xi Q, Huangfu D, Hadjantonakis AK, Massagué J. The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells. Cell Stem Cell. 2017 Jan 5;20(1):70-86. doi: 10.1016/j.stem.2016.10.002.

González F, Huangfu D. Mechanisms underlying the formation of induced pluripotent stem cells. Wiley Interdiscip Rev Dev Biol. 2016 Jan-Feb;5(1):39-65. doi: 10.1002/wdev.206. Review.

Zhu, Z., Verma, N., González, F., Shi, Z. D., & Huangfu, D. (2015). A CRISPR/Cas-Mediated Selection-free Knockin Strategy in Human Embryonic Stem Cells. Stem Cell Reports[PMID: 26028531]

Benitah, S. A., Bracken, A., Dou, Y., Huangfu, D., Ivanova, N., Koseki, H., … & Xu, G. L. (2014). Stem cell epigenetics: looking forward. Cell stem cell14(6), 706-709. [PMID: 25032261]

Zhu, Z., González, F., & Huangfu, D. (2014). The iCRISPR platform for rapid genome editing in human Pluripotent Stem Cells. Methods in enzymology546, 215. [PMID: 25398343]

Kotini, A. G., Chang, C. J., Boussaad, I., Delrow, J. J., Dolezal, E. K., Nagulapally, A. B., … & Papapetrou, E. P. (2015). Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells. Nature biotechnology [PMID: 25798938]

González F, Zhu Z, Shi ZD, Lelli K, Verma N, Li QV, Huangfu D. An iCRISPR Platform for Rapid, Multiplexable, and Inducible Genome Editing in Human Pluripotent Stem Cells. Cell Stem Cell. 2014 Jun 11;S1934-5909(14)00205-7.

Gonzalez F, Georgieva D, Vanoli F, Shi Z-D, Stadtfeld M, Ludwig T, Jasin M, Huangfu D. Homologous Recombination DNA Repair Genes Play a Critical Role in Reprogramming to a Pluripotent State. Cell Reports 2013;3(3):651-660.

Zhu Z, Huangfu D. Human pluripotent stem cells: an emerging model in developmental biology. Development. 2013;140(4):705-717.

Salpeter SJ, Klein AM, Huangfu D, Grimsby J, Dor Y. Glucose and aging control the quiescence period that follows pancreatic beta cell replication. Development. 2010;137(19):3205-13.

Ichida J. K., Blanchard J., Lam K., Son E. Y., Chung J. E., Egli D., Loh K. M., Carter A. C., Di Giorgio F. P., Koszka K., Huangfu D., et al. A Small-Molecule Inhibitor of Tgf-beta Signaling Replaces Sox2 in Reprogramming by Inducing Nanog. Cell Stem Cell. 2009;5(5)491-503.

Huangfu D., Osafune K., Maehr R., Guo W., Eijkelenboom A., Chen S., et al. Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat Biotechnol. 2008;26(11):1269-1275.

Huangfu D., Maehr R., Guo W., Eijkelenboom A., Snitow M., Chen A. E., et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol. 2008;26(7):795-797.

Brennand K., Huangfu D. and Melton D. All beta Cells Contribute Equally to Islet Growth and Maintenance. PLoS Biol. 2007;5(7):e163.

Huangfu D. and Anderson K. V. Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates. Development. 2006;133(1):3-14.

Huangfu D. and Anderson K. V. Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A. 2005;102(32):11325-11330.

Garcia-Garcia M. J., Eggenschwiler J. T., Caspary T., Alcorn H. L., Wyler M. R., Huangfu D., et al. Analysis of mouse embryonic patterning and morphogenesis by forward genetics. Proc Natl Acad Sci U S A. 2005;102(17):5913-5919.

Huangfu D., Liu A., Rakeman A. S., Murcia N. S., Niswander L. and Anderson K. V. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature. 2003;426(6962):83-87.

Caspary T., Garcia-Garcia M. J., Huangfu D., Eggenschwiler J. T., Wyler M. R., Rakeman A. S., et al. Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling. Curr Biol. 2002;12(18):1628-1632.