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The Danwei Huangfu Lab: Publications

Visit PubMed for a full listing of Danwei Huangfu’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Select Research Articles Since 2013

TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells. Verma N, Pan H, Doré LC, Shukla A, Li QV, Pelham-Webb B, Teijeiro V, González F, Krivtsov A, Chang CJ, Papapetrou EP, He C, Elemento O, Huangfu D. Nat Genet. 2018 Jan;50(1):83-95.

Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. Shi ZD, Lee K, Yang D, Amin S, Verma N, Li QV, Zhu Z, Soh CL, Kumar R, Evans T, Chen S, Huangfu D. Cell Stem Cell. 2017 May 4;20(5):675-688.e6. 

The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells. Wang Q, Zou Y, Nowotschin S, Kim SY, Li QV, Soh CL, Su J, Zhang C, Shu W, Xi Q, Huangfu D, Hadjantonakis AK, Massagué J. Cell Stem Cell. 2017 Jan 5;20(1):70-86. doi: 10.1016/j.stem.2016.10.002.

Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes. Zhu Z, Li QV, Lee K, Rosen BP, González F, Soh CL, Huangfu D. Cell Stem Cell. 2016 Jun 2;18(6):755-68. doi: 10.1016/j.stem.2016.03.015. Epub 2016 Apr 28.

A CRISPR/Cas-Mediated Selection-free Knockin Strategy in Human Embryonic Stem Cells. Zhu Z, Verma N, González F, Shi ZD, Huangfu D. Stem Cell Reports. 2015 Jun 9;4(6):1103-11. doi: 10.1016/j.stemcr.2015.04.016. Epub 2015 May 28.

Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells. Kotini A. G., Chang C. J., Boussaad I., Delrow J. J., Dolezal E. K., Nagulapally A. B., … & Papapetrou E. P. (2015). Nature Biotechnol. 

The iCRISPR platform for rapid genome editing in human pluripotent stem cells. González F, Zhu Z, Shi ZD, Lelli K, Verma N, Li QV, Huangfu D. Cell Stem Cell. 2014 Jun 11;S1934-5909(14)00205-7.

Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state. Gonzalez F, Georgieva D, Vanoli F, Shi Z-D, Stadtfeld M, Ludwig T, Jasin M, Huangfu D. Cell Reports 2013;3(3):651-660.

Select Reviewed Articles since 2013

CRISPR/Cas9-Based Engineering of the Epigenome. Pulecio J, Verma N, Mejía-Ramírez E, Huangfu D, Raya A. Cell Stem Cell. 2017 Oct 5;21(4):431-447. Review.

Human pluripotent stem cells: an emerging model in developmental biology. Zhu Z, Huangfu D. Development. Review. 2013;140(4):705-717.