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MSK physician-scientists Michael Glickman and Gil Redelman-Sidi
The ABCs of BCG: Oldest Approved Immunotherapy Gets New Explanation

BCG has been used to treat bladder cancer for more than 30 years. Scientists are still learning how it works.
An illustration of sugar being sprinkled on a cancer cell.
In the Lab
Just Add Sugar: How a Protein’s Small Change Leads to Big Trouble for Cells

A study from investigators in the Sloan Kettering Institute uncovers the details of how a key protein called GRP94 becomes disrupted, leading to cancer and other diseases.
Confocal microscopy image of a female fruit fly brain.
In the Lab
How Fruit Flies Know When They've Mated

Research from investigators at the Sloan Kettering Institute shows how a brain circuit controls mating behavior in fruit flies.
CT scan showing lymphoma in the abdomen between the liver and the gallbladder.
In the Lab
A Metabolic Enzyme Drives Lymphoma and Is a Potential Drug Target

New research from Sloan Kettering Institute investigators pinpoints altered cell metabolism as a cause of B cell lymphoma.
Fluorescent image of CAR T cells in mouse liver fibrosis
In the Lab
A New Target for CAR T Cells: Senescence-Related Diseases

From atherosclerosis and diabetes to liver fibrosis and osteoarthritis, senescent cells are at the root of many debilitating diseases. Scientists increasingly have them in the crosshairs.
Mohita Tagore, a postdoctoral fellow in the Sloan Kettering Institute
Q&A
Meet Mohita Tagore, Winner of a Kravis WISE Postdoctoral Fellowship

Dr. Tagore is a postdoctoral fellow in the Cancer Biology and Genetics Program at the Sloan Kettering Institute studying cell communication in cancer.
MSK leadership on the stage in the Zuckerman Research Center auditorium.
Event
MSK’s Virtual Convocation and Commencement Honors Graduates and Award Winners

Memorial Sloan Kettering’s 41st annual ceremony recognized graduates and award winners with an online event.
X and Y chromosomes in mice
In the Lab
Breaking Up Is Hard to Do (Especially for Sex Chromosomes)

One’s big, one’s small. Somehow, they make it work.
Two gloved hands opening a drawer in a laboratory.
Feature
Double Trouble: Researchers Find Many Cancers Carry Two Mutations in the Same Gene

Discovery reveals that the genetic causes of cancer may be more complicated than previously thought.
A fluorescent image of cells undergoing differentiation in a mouse model.
In Brief
Cancer Stem Cells’ Reliance on a Key Amino Acid Could Be an Exploitable Weakness

The discovery links metabolism to the way cancer stem cells form tumors.