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65 News Items found
Finding
Kenneth Offit and Vijai Joseph
Making an IMPACT: MSK’s Gene-Sequencing Test Reveals New Findings about Hereditary Cancer Risk

An analysis of germline DNA in people with advanced cancer finds that inherited mutations may be more common than expected in this group.
In the Lab
A scientist looks at illustrations of chromosomes.
When Loss Is a Gain: New Tumor Suppressor Gene Identified in Follicular Lymphoma

The reason certain patients with follicular lymphoma do worse than others may come down to a missing gene.
In the Clinic
MSK medical oncologist Luis Diaz, Jr.
The Science Behind the FDA’s Approval of an Immunotherapy for Mismatch Repair–Deficient Cancers

A new paper from MSK physician-scientist Luis Diaz presents the evidence on which the FDA approved the immunotherapy drug pembrolizumab for cancers with a specific genetic abnormality.
Science Byte
Blue cells containing small red dots on a green and black background
Lifeguard on Duty: Looking at DNA Repair under a Microscope

Learn about what DNA repair looks like under a microscope.
In the Lab
Cancer biologist and pediatric oncologist Alex Kentsis
Jumping Genes and the Dark Genome: MSK Researchers Gain New Insight into Childhood Cancers

Researchers have discovered a genetic mechanism that may trigger most childhood cancers.
Mount Rushmore viewed through face-detection software.
Making a Splash: Researchers Apply Face-Detection Technology to the Study of Genes

Taking a cue from smartphone technology, scientists are using face-recognition algorithms to improve RNA interference.
In the Lab
An illustration of CRISPR-Cas9
A Cut Above: MSK-Developed Software Makes CRISPR More Precise

A freely accessible software program provides researchers with an easy way to optimize a popular genome-editing tool.
Feature
Molecular biologist John Petrini of the Sloan Kettering Institute.
Understanding the DNA-Damage “First Responders”: John Petrini at Work

Scientists know that cancer can result from mistakes in DNA repair. But understanding what controls the repair process itself has been a hard nut to crack.
In the Lab
Histology images of stem cells and AML cells
Step by Step: Stem Cell Approach Provides New Models for Studying How Acute Myeloid Leukemia Progresses

A new laboratory tool will allow researchers to study the progression from normal cells to myelodysplastic syndromes to an aggressive type of leukemia.
Announcement
Dr. Joan Massagué, Sloan Kettering Institute Director received the Pezcoller Foundation-AACR International Award for Cancer Research and was named an AACR fellow at AACR16.
News from #AACR16: Targeted Therapy Breakthrough, Improved Survival in Melanoma, and Benefits of Gut Bugs

Long-awaited results of clinical trials testing targeted drugs and immunotherapy combinations were on offer at the annual American Association for Cancer Research (AACR) conference.