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65 News Items found
In the Lab
Pictured: Casper zebrafish
Studying Cancer Mysteries Just Beneath the Scales

Hail to the zebrafish. MSK scientists are using a small fish to answer some big questions about cancer.
In the Lab
Organoid cell structures fluorescing in blue, green, and purple.
Manipulating a Single Gene Turns Colorectal Cancer Cells Back to Normal

For the first time, scientists have shown that the gene APC, which is mutated in the vast majority of colorectal cancers, might be a promising target for future therapies.
In the Lab
Cancer genomics researcher Timothy Chan
Why a New Immunotherapy for Lung Cancer Works for Only Some People

According to an MSK study, a powerful immunotherapy drug for lung cancer works better in people whose tumors carry a lot of mutations caused by tobacco smoke.
In the Lab
MSK investigators Joan Massagué and Anna Obenauf
Outsmarting Cancer’s Survival Skills

A new study led by MSK investigators reveals how some cancer cells become resistant to targeted treatment and suggests what might be done to stop that from happening.
In the Clinic
Pictured: Charles Sawyers
The Evolution of a Lifesaving Drug: A Scientist Reflects

Physician-scientist Charles Sawyers played a pivotal role in the development of Gleevec, one of the first successful targeted drugs for cancer.
In the Clinic
New treatments developed at MSK focus on both common and rare cancers.
Report Highlights Advances Made at MSK That Are Changing Patients’ Lives

An annual report from an influential cancer group highlights three MSK studies that have advanced cancer research.
Finding
MSK investigators Michael Berger and David Solit.
Study Reveals How Some Breast Cancers Become Resistant to Targeted Drugs

A study of one patient’s disease has clarified why tumors stop responding to a class of experimental drugs called PI3K inhibitors.
In the Lab
Pictured: William Lee, Chris Sander & Nils Weinhold
Beyond the Usual Suspects: Study of Noncoding DNA Reveals New Mutations Linked to Cancer

In a study of patient tumor samples, researchers have found common mutations in parts of the genome that control gene regulation.
In the Lab
Cancer biologist Andrea Ventura
Disorderly DNA: Researchers Simulate a Common Cause of Lung Cancer

MSK scientists have created a mouse model that replicates a subtype of non-small cell lung cancer caused by a chromosomal rearrangement.
Decoder
DNA wrapped around histones
What Is Epigenetics?

Physician-scientist Omar Abdel-Wahab explains epigenetics, a growing field based on the study of genetic changes that are not part of the DNA code, and how it relates to cancer.