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291 News Items found
SKI immunologist Andrea Schietinger
Discovery of a Stem-like T Cell in Type 1 Diabetes Holds Potential for Improving Cancer Immunotherapy, Sloan Kettering Institute Scientists Say

As an autoimmune disease, Type 1 diabetes raises important questions about immune cell activity that have broad implications for immunotherapy.
Finding
Yonina Murciano-Goroff, Jenny Xue, Bob Li, Piro Lito, and Yulei Zhao.
MSK Researchers Are Learning Why Some Patients Develop Resistance to Targeted Lung Cancer Drug

A paper from MSK researchers reports that resistance to sotorasib, a new targeted drug for lung cancer, can be caused by many different molecular changes.
Scientists Learn More about How Lung Cancer Becomes Resistant to Drugs

By switching from one cellular identity to another, lung cancer cells can evade targeted therapies. MSK scientists are trying to stop that from happening.
Charles Rudin and Dana Pe'er
Molecular Atlas of Small Cell Lung Cancer Reveals Unusual Cell Type That Could Explain Why It’s So Aggressive

Stem-like cells that make up only a tiny fraction of the total cells in a lung tumor could be the key to stopping the disease’s deadly spread, say researchers at Memorial Sloan Kettering.
Katharine Hsu and Rosa Sottile
Unusual Immune Cell Type Could Be Good Target for Immunotherapy

Part natural killer, part T cell, this hybrid immune cell has a “double sword” for fighting cancer.
Man holding an IUD
To Detect Ovarian Cancer Early, Researchers Look to Nanotechnology

Could an implantable IUD help detect cancer early, when it is most curable? Scientists at the Sloan Kettering Institute are betting yes.
A collage of photos showing a zebrafish with GFP-labeled melanocytes, magnified GFP-labeled melanocytes, and hPSC-derived melanocytes growing in a dish.
Why Are Only Some Cells ‘Competent’ to Form Cancer? MSK Scientists Say Context Is Key

Experiments with zebrafish and human pluripotent stem cells reveal the necessary ingredients, besides genetic mutations, that fuel the development of melanoma.
MSK scientists Margaret Callahan, Ronglai Shen, and Katherine Panageas
MSK Study Identifies Biomarker That May Help Predict Benefits of Immunotherapy

A blood-based test identifies patients in whom immunotherapy may ‘LAG.’
In the Lab
Scientist Gabriela Chiosis in her lab
Experimental Drug Targets Misbehaving Proteins in Brain Cancer and Alzheimer’s Disease

Memorial Sloan Kettering researchers are studying how drugs that reverse malfunctioning proteins may treat disease.
Q&A
Memorial Sloan Kettering surgeon Prasad Adusumilli
CAR T Cell Therapy Shows Promise for Treating Mesothelioma

A combination immunotherapy approach using CAR T cells could be an effective new way to treat mesothelioma.