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Feature
NK cells attacking
Meet the Unsung Immune Cell that Could Change Immunotherapy

A lesser-known immune cell is suddenly getting more attention in the field of cancer immunology.
Finding
A doctor examines a mole.
Don't Scratch That Mole? Scientists Are Learning More about Inflammation and Cancer

It's not only what's inside your cells that determines your cancer risk. It's what surrounds them too.
Feature
Omar Abdel-Wahab
What Is Epigenetics, and Why Is Everyone Talking about It?

The word “epigenetic” literally means “above the genes.” Calico cats demonstrate a type of epigenetic inheritance called X-inactivation.
Finding
Large cells filled with yellow-colored fat
Cancer Cells Eat Fat to Grow and Spread

Research conducted in zebrafish shows that melanoma cells have an affinity for fat, and that eating it makes them more aggressive.
Finding
Scanning electron micrograph (SEM) of T lymphocyte cells (blue) attached to a red cancer cell.
Discovery of Unusual Cell Type Could Help Guide Immunotherapy

A newly identified group of immunosuppressive cells could provide insight into the effects of immunotherapy drugs.
In the Lab
Blue cells containing small red and green dots on a black background
Scientists Pinpoint a New Cause of Resistance to EGFR-Targeting Drugs

Multiple copies of a gene called <em>YES1</em> appear to be responsible for certain precision drugs losing their effectiveness.
In Brief
MSK light bright image
Can You Hear Me Now? Scientists Find Nanoparticles Have a Language of Their Own

Nanoparticles were thought of a silent partner in imaging technologies. They’re now being recognized as an important source of subatomic chatter.
In the Clinic
Medical oncologist Jae Park
Longest-Running CAR T Trial Shows Which Patients Benefit Most, Have Fewest Side Effects

The study represents 20 years of research at MSK.
In the Lab
abstract red and blue lines suggestive of metabolic pathways
Scientists Create First-of-Its-Kind Metabolic Road Map of Cancer

The online resource will serve as a benchmark for researchers studying metabolism and cancer.
In the Lab
A gray blob marked RAS linked to colorful rods marked ICMT
Deciphering How Membrane Enzymes Work, with a Little Help from Beetles

The atomic structure of an elusive type of membrane protein has finally been solved by scientists at the Sloan Kettering Institute.