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Emily Kansler, PhD

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Emily Kansler

Email

[email protected]

Dissertation

An Innate Lymphocyte Cancer Cell Sensing Program Governs Immunosurveillance of Human and Murine Malignancies. (2021)

Mentor

Start Year

2015

End Year

2021

Education

BS, Salisbury University; ScM, Johns Hopkins University

My broad research interests lie in the regulation of the immune system and tumor immunology. Outside of Gerstner Sloan Kettering and the lab, most of my hobbies require the outdoors. I love Central Park and the endless places to explore in New York City — each area is unique. When I’m not in the city, I am hiking, camping, or traveling.

Fellowships

Olayan Fellowship (2016-2017)

Publications

Kansler ER, Dadi S, Krishna C, Nixon BG, Stamatiades EG, Liu M, Kuo F, Zhang J, Zhang X, Capistrano K, Blum KA, Weiss K, Kedl RM, Cui G, Ikuta K, Chan TA, Leslie CS, Hakimi AA, Li MO. (2022) Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies. Nat Immunol. 6; 904-915;

Chou C, Zhang X, Krishna C, Nixon BG, Dadi S, Capistrano KJ, Kansler ER, Steele M, Han J, Shyu A, Zhang J, Stamatiades EG, Liu M, Li S, Do MH, Edwards C, Kang DS, Chen CT, Wei IH, Pappou EP, Weiser MR, Garcia-Aguilar J, Smith JJ, Leslie CS, Li MO. (2022) Programme of self-reactive innate-like T cell-mediated. Nature 605. 139-145

Nixon BG, Chou C, Krishna C, Dadi S, Michel AO, Cornish AE, Kansler ER, Do MH, Wang X, Capistrano KJ, Rudensky AY, Leslie CS, Li MO. (2022) Cytotoxic granzyme C-expressing ILC1s ontribute to antitumor immunity and neonatal autoimmunity. Sci Immunol. Epub.

Kansler ER, Li MO. (2019) Innate lymphocytes-lineage, localization and timing of differentiation. Cell Mol Immunol. doi: 10.1038/s41423-019-0211-7. [Epub ahead of print].

Kansler ER, Verma A, Langdon EM, Simon-Vermot T, Yin A, Lee W, Attiyeh M, Elemento O, White RM. (2017)Melanoma genome evolution across species. BMC Genomics. 18, 136. PMCID: PMC5297047

Kim IS, Heilmann S, Kansler ER, Zhang Y, Zimmer M, Ratnakumar K, Bowman RL, Simon-Vermot T, Fennell M, Garippa R, Lu L, Lee W, Hollmann T, Xavier JB, White RM. (2017) Microenvironment-derived factors driving metastatic plasticity in melanoma. Nat Commun. 8, 14343. PMCID: PMC5309794

Kansler ER, Verma A, Langdon EM, Simon-Vermot T, Yin A, Lee W, Attiyeh M, Elemento O, White RM. Melanoma genome evolution across species. BMC Genomics 18, 136. PMCID: PMC5297047

Heilmann S, Ratnakumar K, Langdon EM, Kansler ER, Kim IS, Campbell NR, Perry EB, McMahon AJ, Kaufman CK, van Rooijen E, Lee W, Iacobuzio-Donahue CA, Hynes RO, Zon LI, Xavier JB, White RM. (2015) A Quantitative System for Studying Metastasis Using Transparent Zebrafish. Cancer Res. 75, 4272-82. PMCID: PMC4609292

Krishna C, DiNatale RG, Kuo F, Srivastava RM, Vuong L, Chowell D, Gupta S, Vanderbilt C, Purohit TA, Liu M, Kansler E, Nixon BG, Chen YB, Makarov V, Blum KA, Attalla K, Weng S, Salmans ML, Golkaram M, Liu L, Zhang S, Vijayaraghavan R, Pawlowski T, Reuter V, Carlo MI, Voss MH, Coleman J, Russo P, Motzer RJ, Li MO, Leslie CS, Chan TA, Hakimi AA. (2021) Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy. Cancer Cell. 39., 662-677

Chou C, Zhang X, Krishna C, Nixon BG, Dadi S, Capistrano KJ, Kansler ER, Steele M, Han J, Shyu A, Zhang J, Stamatiades EG, Liu M, Li S, Do MH, Edwards C, Kang DS, Chen CT, Wei IH, Pappou EP, Weiser MR, Garcia-Aguilar J, Smith JJ, Leslie CS, Li MO. (2022) Programme of self-reactive innate-like T cell-mediated. Nature 605. 139-145

Nixon BG, Chou C, Krishna C, Dadi S, Michel AO, Cornish AE, Kansler ER, Do MH, Wang X, Capistrano KJ, Rudensky AY, Leslie CS, Li MO. (2022) Cytotoxic granzyme C-expressing ILC1s ontribute to antitumor immunity and neonatal autoimmunity. Sci Immunol. Epub.