Cancer Biology & Genetics Program
The Mara Sherman Lab
Research
Associate Professor
The Mara Sherman lab aims to understand the heterocellular interactions among pancreatic cancer cells and their surrounding microenvironment, and to target these networks for therapeutic benefit. Our research focuses on the tumor-permissive molecular mechanisms underlying cancer-associated fibroblast function as well as immune suppression, and how these stromal mechanisms affect cell fate and function in the pancreatic epithelium with respect to gene expression, metabolism, and cancer cell state. Our laboratory uses a multidisciplinary approach to investigate the mechanistic underpinnings of the pancreatic tumor microenvironment, including mouse models of pancreatic cancer, three-dimensional cell culture systems such as patient-derived organoids, and diverse molecular- and cell-biological techniques enabling investigation of the mechanisms underlying tumor-stroma interaction.
Research Projects
People
Mara Sherman, PhD
Associate Professor
- The Mara Sherman lab aims to understand the heterocellular interactions among pancreatic cancer cells and their surrounding microenvironment, and to target these networks for therapeutic benefit.
- PhD, University of California, Los Angeles
- [email protected]
- Email Address
Members
Postdoctoral Fellow
Staff Scientist
Postdoctoral Fellow
Research Fellow
Research Lab Manager
Graduate Student
Research Assistant
Administrative Assistant
Graduate Student
Lab Affiliations
Achievements
- Lustgarten Foundation Therapeutics Focused Research Program awardee (2021)
- Pew-Stewart Scholar Award (2020)
- American Cancer Society Research Scholar Grant (2018)
- V Foundation V Scholar Award (2017)
- NIH/NCI K99/R00 Pathway to Independence Award (2015)