Journal Club 2021

Journal Club 2021

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November 2021

11/18/21

Presented by Kristen Vogt

“Brain capillary obstruction as a novel mechanism of anti-CD19 CAR T cell neurotoxicity.”

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October 2021

10/28/21

Presented by Manish Malviya

“Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment.”

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10/14/21

Presented by Zita Aretz

“Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.”

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September 2021

9/30/21

Presented by Pedro Silberman

“Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors.”Article Link


9/16/21

Presented by James Han

“Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade.”

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9/09/2021

Presented by Heather Jones

“HLA-E-restricted HIV-1-specific CD8+ T cell responses in natural infection.”

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August 2021

8/12/2021

Presented by Chris Bourne

“Pooled screening of CAR T cells identifies non-native signaling domains for next-generation immunotherapies.”

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July 2021

7/29/2021

Presented by Keifer Kurtz

“Gene-engineered exosomes-thermosensitive liposomes hybrid nanovesicles by the blockade of CD47 signal for combined photothermal therapy and cancer immunotherapy.”

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7/15/2021

Presented by Kristen Vogt

“Investigation of product derived lymphoma following infusion of piggyBac modified CD19 chimeric antigen receptor T-cells.”

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7/08/2021

Presented by Manish Malviya

“Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease.”

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7/01/2021

Presented by Heather Jones

“TAP dysfunction in dendritic cells enables noncanonical cross-presentation for T cell priming.”

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June 2021

6/04/2021

Presented by Zita Aretz

“Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity.”

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May 2021

5/21/2021

Presented by Zaki Molvi

“CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity.”

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April 2021

4/16/2021

Presented by Pedro C. Silberman

“Senolytic CAR T cells reverse senescence-associated pathologies.”

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4/09/2021

Presented by Christopher Bourne

“AAV-Mediated In Vivo CAR Gene Therapy for Targeting Human T Cell Leukemia.”

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March 2021

3/19/2021

Presented by Keifer Kurtz

“Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection.”

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3/05/2021

Presented by Leila Peraro

“Engineering Tolerance toward Allogeneic CAR-T Cells by Regulation of MHC Surface Expression with Human Herpes Virus-8 Proteins.”

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Presented by Kristen Vogt

“Regulatory T cells engineered with TCR signaling–responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter.”

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February 2021

2/19/2021

Presented by Megan Dacek

“Modeling human adaptive immune responses with tonsil organoids.”

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2/05/2021

Presented by Manish Malviya

“Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells.”Article link

January 2021

1/29/2021

Presented by Heather Jones

“Antigen identification for HLA class I– and HLA class II–restricted T cell receptors using cytokine-capturing antigen-presenting cells.”

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