The Alexandros Pertsinidis Lab

The Alexandros Pertsinidis Lab

Our mission is the development of a “new” generation of optical imaging technologies to enable advances in two hitherto difficult-to-investigate areas: the real-time analysis of macromolecular interactions and motions at the nanometer scale in vivo and the three-dimensional architecture of complex molecular machines and of subcellular ultrastructure, in situ. We are also refining and applying ultrahigh-resolution spectroscopy techniques to dissect multistep complex biochemical processes using in vitro reconstituted single-molecule assays.

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Alexandros Pertsinidis, PhD

Alexandros Pertsinidis, PhD

Associate Professor

Research Focus

The Pertsinidis laboratory uses single-molecule approaches to understand gene transcription and the function of complex macromolecular machines inside live cells.


PhD, Brown University
Selected Achievements
  • Director’s New Innovator Award, National Institutes of Health (2012)