Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy. 2022. Xie XP, Laks DR, Sun D, Ganbold M, Wang Z, Pedraza AM, Bale T, Tabar V, Brennan C, Zhou X, Parada LF. 2022, Dev Cell, PMCID: PMC8820651.
Stem-like cells drive NF1-associated MPNST functional heterogeneity and relapse after chemotherapy. 2021. Sun D, Xie X, Wang Z, Sait S, Iyer S, Chen Y, Brown R, Laks D, Chipman M, and Parada L. 2021, Cell Stem Cell, PMCID: PMC8349880
High resolution mouse subventricular zone stem cell niche transcriptome reveals features of lineage, anatomy, and aging. Xie XP, Laks DR, Sun D, Poran A, Laughney AM, Wang Z, Sam J, Belenguer G, Fariñas I, Elemento O, Zhou X, Parada LF., 2020. Proceedings of the National Academy of Sciences. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31448-31458. doi: 10.1073/pnas.2014389117. Epub 2020 Nov 23.
Cell Lineage-Based Stratification for Glioblastoma. Wang Z, Sun D, Chen YJ, Xie X, Shi Y, Tabar V, Brennan CW, Bale TA, Jayewickreme CD, Laks DR, Alcantara Llaguno S, Parada LF. Cancer Cell. 2020 Sep 14;38(3):366-379.e8. doi: 10.1016/j.ccell.2020.06.003. Epub 2020 Jul 9. PMID: 32649888; PMCID: PMC7494533.
Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Shi Y, Lim SK, Liang Q, Iyer SV, Wang HY, Wang Z, Xie X, Sun D, Chen YJ, Tabar V, Gutin P, Williams N, De Brabander JK, Parada LF. Nature. 2019 Mar;567(7748):341-346. doi: 10.1038/s41586-019-0993-x. Epub 2019 Mar 6.