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A gray blob marked RAS linked to colorful rods marked ICMT
In the Lab
Deciphering How Membrane Enzymes Work, with a Little Help from Beetles

The atomic structure of an elusive type of membrane protein has finally been solved by scientists at the Sloan Kettering Institute.
A barred Plymouth Rock hen
Feature
How a Chicken Helped Solve the Mystery of Cancer

When this feathered patient found her way into a New York laboratory in 1909, she changed the course of cancer science.
Gears with 2016 and 2017
In the News
Year in Review: The Science and Technology that Shaped Cancer Care in 2017

As 2017 draws to a close, take a look back at the scientific discoveries that deepened our understanding of cancer in the past year.
Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh
In the Lab
When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.
A microscopic view of genetically engineered mouse tumor and a human FL-HCC tumor
In the Lab
With Help of CRISPR, Scientists Unravel the Cause of a Rare Liver Cancer

A team led by MSK molecular biologist Scott Lowe is making progress against fibrolamellar hepatocellular carcinoma.
Zeda Zhang
Honors
GSK Student Wins NCI Award to Pursue Innovative Prostate Cancer Research

Zeda Zhang was recently awarded the Predoctoral to Postdoctoral Fellow Transition Award from the National Cancer Institute (NCI).
Prostate cancer cells, colored red in scanning electron micrograph (SEM).
Science Byte
PSMA: A New Target for Prostate Cancer Treatment

Researchers have discovered how a high level of the protein PSMA in cells helps fuel prostate cancer.
iron-filled macrophages from a breast cancer tumor
In the Lab
MSK-Developed Technology Provides a “Virtual Biopsy” of Immune Cells in Tumors

The noninvasive approach could help scientists track the movements of an important cell type that can influence the outcome of cancer treatment.
Cancer biologist and pediatric oncologist Alex Kentsis
Science Byte
Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers

A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.
Image of DNA helix with sequence in the background
In the Clinic
Genetic ‘Scars’ Provide Clues for Tailoring Cancer Treatment

For the first time, scientists have determined the extent of DNA repair deficiencies across cancer types. Learn what it means for patients.