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In the News
AACR 2019 Annual Meeting
AACR 2019 Research Roundup: Pancreatic Cancer Immunotherapy, Prostate Cancer Drug Resistance, Insight into Inherited Cancer Mutations

Read up on the latest developments in several important areas of cancer research emerging from the 2019 American Association for Cancer Research annual meeting.
In the Lab
Enhanced MRI of a glioblastoma
Starving Cancer Stem Cells Could Be the Trick to Treating Glioblastoma, Study Finds

MSK researchers have identified a compound that kills glioblastoma cells using a mechanism that’s completely different from earlier treatments.
Finding
Alex Kentsis in his lab
Research Uncovers the Genetic Causes of Aggressive Leukemia in Children

Researchers have found that the genetic changes that cause pediatric leukemia are different from those that lead to leukemia in adults.
In the Clinic
Image of a mobile phone with a strand of DNA
There’s an App for That: When the Meaning of a BRCA Mutation Isn’t Clear-Cut

A new project called the BRCA Exchange is sharing data about BRCA mutations and what they actually mean for cancer risk.
In the Lab
electron micrograph of a natural killer cell
Drugs That Stall — But Don’t Kill — Cancer Cells Are an Untapped Resource, Study Suggests

A drug combination that halts tumor cell division can stir the immune system into taking action.
In the Clinic
A tube of blood superimposed on a lung and a DNA helix
Liquid Biopsy Is Effective at Guiding Treatment of Lung Cancer, Study Finds

The initial results of an ongoing study show that a liquid biopsy has advantages over a tissue biopsy for people with lung cancer.
In the Lab
Sloan Kettering Institute molecular biologist Christine Mayr
Scientists Find Cancer Drivers Hiding in a New Place

New findings from researchers at the Sloan Kettering Institute suggest that cancer causes may be lurking in the molecule that bridges DNA and protein.
In the Lab
This image shows cancer cells (white) and pericytes (green) clinging to capillaries (red). The blue dots are nuclei.
Scientists Identify Growth Signal for Metastatic Cancer "Seeds"

Targeting this signal with drugs might be one way to stop cancers from spreading.
In the Lab
A microscopic view of genetically engineered mouse tumor and a human FL-HCC tumor
With Help of CRISPR, Scientists Unravel the Cause of a Rare Liver Cancer

A team led by MSK molecular biologist Scott Lowe is making progress against fibrolamellar hepatocellular carcinoma.
Science Byte
Cancer biologist and pediatric oncologist Alex Kentsis
Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers

A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.