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In the Lab
Fluorescent image of CAR T cells in mouse liver fibrosis
A New Target for CAR T Cells: Senescence-Related Diseases
From atherosclerosis and diabetes to liver fibrosis and osteoarthritis, senescent cells are at the root of many debilitating diseases. Scientists increasingly have them in the crosshairs.
In the Clinic
Scientific Image
CAR Therapy for Solid Tumors Draws Attention at Annual Cancer Conference
Results from a clinical trial indicate that an experimental CAR therapy for mesothelioma is safe.
In the Lab
MSK Scientists Build "Armored" CAR T Cells to Smite Solid Tumors
The engineered immune cells secrete powerful drugs as a layer of defense.
Feature
MSK cell manufacturing specialist Xiuyan Wang
Meet the Scientists Who Engineer CAR T Cells, a Type of "Living" Immunotherapy
An immunotherapy called CAR T is transforming the treatment of certain cancers. These are the people who make it possible.
In the Lab
CAR T cells attacking cancer
CRISPR Genome-Editing Tool Takes Cancer Immunotherapy to the Next Level
What do you get when you combine two of the hottest areas of biotechnology? A new paper from MSK researchers explains.
In the Lab
Fibrous extensions of a nerve cell (red) and an oligodendrocyte (green) growing on top of the nerve cell
Can Stem Cells Be Taught to Repair a Radiation-Damaged Brain?
In a recent study, Memorial Sloan Kettering scientists used stem-cell engineering to repair brain injuries in rats. The results raise hope for future therapies that could prevent or fix nerve damage in cancer patients who need brain radiation.
In the Clinic
New treatments developed at MSK focus on both common and rare cancers.
Report Highlights Advances Made at MSK That Are Changing Patients’ Lives
An annual report from an influential cancer group highlights three MSK studies that have advanced cancer research.
In the Lab
Neurons created from embryonic stem cells
Seeing the Light: How Engineered Nerve Cells Might Curb Parkinson’s Disease
A new tool called optogenetics is revealing clues about the function of a promising experimental therapy derived from stem cells.
Finding
Michel Sadelain and Prasad Adusumilli
Immunotherapy Shows Promise for Treating Solid Tumors in the Chest
A study in mouse models suggests how modified T cells may be used to treat tumors in the area just outside the lungs.
In the Lab
Pictured: Experimental Brain Tumor
Genetic “Kill Switch” Could Make Cell Therapies Safer
Researchers have engineered a gene into therapeutic cells that allows them to turn off tumor growth if some of the cells become cancerous.