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Memorial Sloan Kettering immunologist Frederic Geissmann
Feel the Burn: Researchers Identify Fat Storage Protein That Could Be Key to Alleviating Obesity

Researchers discover how immune cells called macrophages regulate whether fat is stored or burned.
MSK Scientists Reveal Biology of Shape-Shifting Lung Cancer

Lung cancer has an uncanny ability to change its identity to resist drugs. Researchers are learning what drives these changes.
Feature
Group photo of researchers Michael Berger, Marc Ladanyi, Dana Tsui, Rose Brannon, Ryma Benayed, Ahmet Zehir, and David Klimstra.
How MSK-ACCESS Blood Test for Cancer was Created

MSK-ACCESS, a blood test that can detect mutations in 129 genes related to cancer, has already helped guide the treatment of more than 2,800 patients at MSK.
In the Lab
Physician-scientist Omar Abdel-Wahab
Research Suggests How Boosting Neoantigens Can Make Immunotherapy More Effective

In mice, drugs that change the way proteins are assembled appear to make checkpoint inhibitor drugs work better.
MSK computational biologist Sohrab Shah
Scientists Obtain Real-Time Look at How Cancers Evolve

With the help of machine learning, computational biologists are learning to predict how cancers will evolve.
Finding
Zsofia Stadler
Knowledge of Inherited Gene Mutations Increasingly Can Guide Cancer Treatment

An analysis of patients who received molecular testing at MSK has found that about half of those with hereditary gene mutations could benefit from treatment with therapies that target those alterations.
SKI immunologist Michael Glickman
MSK Scientists Solve One of TB’s Deadliest Tricks

Scientists at Memorial Sloan Kettering have pieced together the biochemical mechanism by which the tuberculosis bacterium sneaks past our immune defenses.
In the Lab
Developmental biologist Luis Parada
Stem Cells May Explain Why Rare Inherited Tumor in Kids Is So Aggressive

Sloan Kettering Institute investigators have found that a subpopulation of cells within a type of sarcoma called malignant peripheral nerve sheath tumor appear to be similar to a type of neural stem cells.
In the Lab
Structural biologist Stephen Long in his lab
High-Tech Microscope Reveals Inner Workings of Protein Assembly Machinery

Sloan Kettering Institute investigators have learned how Hedgehog proteins, which are important in both development and cancer, are assembled.
Five MSK researcher headshots
ASCO 2021 Research Roundup: Focus on Immunotherapy

Read about the latest findings in immunotherapy from the 2021 annual meeting of the American Society of Clinical Oncology (ASCO).