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30 News Items found
Finding
MSK investigators Michael Berger and David Solit.
Study Reveals How Some Breast Cancers Become Resistant to Targeted Drugs

A study of one patient’s disease has clarified why tumors stop responding to a class of experimental drugs called PI3K inhibitors.
In the Lab
Pictured: Ping Chi
Molecular Studies Provide New Clues about Rare Soft Tissue Sarcoma

Genetic analysis reveals biomarkers and possible drug targets for malignant peripheral nerve sheath tumors.
In the Lab
Pictured: Scott Lowe
Researchers Uncover Potential Target for “Undruggable” Form of Liver Cancer

In taking a new approach to finding treatments for hepatocellular carcinoma, MSK scientists have uncovered a potential drug target for this highly aggressive cancer.
In the Lab
An origami crane illustrates the importance of RNA folding for regulating gene translation. The bolded sequences on the crane’s wings indicate the portion that is critical for the manufacture of many cancer-causing proteins.
Compound from Tropical Plant Targets Key Cancer-Causing Genes

Memorial Sloan Kettering researchers have found a naturally occurring compound that can destroy cancer cells in mice by targeting <em>MYC</em>, a cancer-causing gene that has remained elusive until now.
Finding
Pictured: Gabriela Chiosis
Hsp90: A Very Promising Target for Cancer Therapy

A small molecule discovered at MSK called PU-H71 blocks the growth of cancer cells and enables doctors to image tumors.
In the Lab
Pictured: Three-dimensional structure of the protein mTOR
A Recently Revealed Protein Structure Creates New Opportunities for Cancer Research and Drug Design

In an eagerly awaited study, Memorial Sloan Kettering researchers report on the molecular structure of mTOR, a protein commonly mutated in cancer.
In the Lab
Pictured: Charles Sawyers
Research Suggests a New Approach for Overcoming Resistance to a Targeted Therapy for Prostate Cancer

Research suggests that a new drug could be effective in patients with prostate cancer who develop resistance to the targeted therapy enzalutamide.
In the Lab
Pictured: PET Scan
New Imaging Agent Could Improve Prostate Cancer Diagnosis and Treatment

Researchers at Memorial Sloan Kettering are developing a new strategy for PET imaging of tumors that could result in new tools to detect and monitor prostate cancer.
In the Lab
Pictured: Structural formula of IBNtxA
Findings Could Lead to the Development of a New Painkiller

Scientists have generated a compound that could potentially be used to create a new type of pain medication that may prevent the side effects of currently available painkillers.
Media Advisory
Pictured: David Solit
Researchers Discover Why New Melanoma Drug Stops Working

Research led by investigators at Memorial Sloan Kettering has identified a previously unknown mechanism of resistance to the newly approved melanoma drug, vemurafenib.