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65 News Items found
In the Lab
photo of Foxo1 protein stained in regulatory T cells
In the Fight against Cancer, the Immune System Can Be a Double-Edged Sword
The immune system is a powerful tool for fighting cancer — sometimes too powerful.
In the Lab
MSK investigators Joan Massagué and Anna Obenauf
Outsmarting Cancer’s Survival Skills
A new study led by MSK investigators reveals how some cancer cells become resistant to targeted treatment and suggests what might be done to stop that from happening.
In the Clinic
Pictured: Charles Sawyers
The Evolution of a Lifesaving Drug: A Scientist Reflects
Physician-scientist Charles Sawyers played a pivotal role in the development of Gleevec, one of the first successful targeted drugs for cancer.
In the Clinic
New treatments developed at MSK focus on both common and rare cancers.
Report Highlights Advances Made at MSK That Are Changing Patients’ Lives
An annual report from an influential cancer group highlights three MSK studies that have advanced cancer research.
Finding
Michel Sadelain and Prasad Adusumilli
Immunotherapy Shows Promise for Treating Solid Tumors in the Chest
A study in mouse models suggests how modified T cells may be used to treat tumors in the area just outside the lungs.
Finding
MSK investigators Michael Berger and David Solit.
Study Reveals How Some Breast Cancers Become Resistant to Targeted Drugs
A study of one patient’s disease has clarified why tumors stop responding to a class of experimental drugs called PI3K inhibitors.
Decoder
DNA wrapped around histones
What Is Epigenetics?
Physician-scientist Omar Abdel-Wahab explains epigenetics, a growing field based on the study of genetic changes that are not part of the DNA code, and how it relates to cancer.
In the Lab
Pictured: Ping Chi
Molecular Studies Provide New Clues about Rare Soft Tissue Sarcoma
Genetic analysis reveals biomarkers and possible drug targets for malignant peripheral nerve sheath tumors.
In the Lab
Pictured: Experimental Brain Tumor
Genetic “Kill Switch” Could Make Cell Therapies Safer
Researchers have engineered a gene into therapeutic cells that allows them to turn off tumor growth if some of the cells become cancerous.
Finding
Pictured: Gabriela Chiosis
Hsp90: A Very Promising Target for Cancer Therapy
A small molecule discovered at MSK called PU-H71 blocks the growth of cancer cells and enables doctors to image tumors.