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82 News Items found
Finding
Blue cancer cell with a target on it
Adding Low-Dose Radiation Could Make CAR T Therapy More Effective, Study Finds

The treatment combination appears to boost chimeric antigen receptor (CAR) T cells’ ability to kill cancer cells in solid tumors.
In the Lab
Different viewpoints of the STING pathway
Putting the STING in Immunotherapy: Research Focuses on Ways to Improve Cancer Treatments

Researchers are looking for ways to make cancer cells more visible to the immune system.
Feature
MSK cell manufacturing specialist Xiuyan Wang
Meet the Scientists Who Engineer CAR T Cells, a Type of "Living" Immunotherapy

An immunotherapy called CAR T is transforming the treatment of certain cancers. These are the people who make it possible.
Feature
Omar Abdel-Wahab
What Is Epigenetics, and Why Is Everyone Talking about It?

The word “epigenetic” literally means “above the genes.” Calico cats demonstrate a type of epigenetic inheritance called X-inactivation.
Finding
Scanning electron micrograph (SEM) of T lymphocyte cells (blue) attached to a red cancer cell.
Discovery of Unusual Cell Type Could Help Guide Immunotherapy

A newly identified group of immunosuppressive cells could provide insight into the effects of immunotherapy drugs.
In the Lab
Blue cells containing small red and green dots on a black background
Scientists Pinpoint a New Cause of Resistance to EGFR-Targeting Drugs

Multiple copies of a gene called <em>YES1</em> appear to be responsible for certain precision drugs losing their effectiveness.
In the Clinic
Medical oncologist Jae Park
Longest-Running CAR T Trial Shows Which Patients Benefit Most, Have Fewest Side Effects

The study represents 20 years of research at MSK.
Feature
A barred Plymouth Rock hen
How a Chicken Helped Solve the Mystery of Cancer

When this feathered patient found her way into a New York laboratory in 1909, she changed the course of cancer science.
In the Lab
iron-filled macrophages from a breast cancer tumor
MSK-Developed Technology Provides a “Virtual Biopsy” of Immune Cells in Tumors

The noninvasive approach could help scientists track the movements of an important cell type that can influence the outcome of cancer treatment.
Science Byte
Cancer biologist and pediatric oncologist Alex Kentsis
Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers

A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.