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I am a physician-scientist specializing in gastrointestinal (GI) cancers, with a strong focus on the cancer-microbiome-immune axis. Trained in medical oncology at the University of Paris La Sorbonne and specialized in GI malignancies at the Curie Institute, France, I have led research exploring the role of intratumoral bacteria in tumor heterogeneity and immune modulation. My work has demonstrated that Fusobacterium nucleatum is a favorable prognostic factor in squamous cell carcinomas and linked microbial diversity to immune markers in cancer. I also investigate microbiota in metastases, collaborating with the French National Cancer Institute (INCa) and MSKCC to explore how targeting tumor-associated bacteria can enhance anticancer immune responses. At MSKCC, I lead research on mechanisms of resistance and response to combined PARP and PD-1 inhibition in pancreatic cancer, leveraging single-cell RNA sequencing and spatial proteomics. My expertise spans digital pathology, genomics, immunology, and bioinformatics, bridging translational science with clinical oncology to develop novel therapeutic strategies.