The Simon Powell Lab

The Simon Powell Lab

The major theme of our work is how DNA repair processes are disrupted in human cancers and how this can be exploited therapeutically. The biologically significant DNA damage caused by ionizing radiation and a number of cytotoxic drugs requires double-strand break repair for survival. We have largely focused on the role of double-strand break repair and homologous recombination in particular.

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Simon N. Powell, MD, PhD

Simon N. Powell, MD, PhD


Research Focus

Molecular biologist Simon Powell investigates DNA replication and recombination, chromosome dynamics, and human genetics.


PhD, MD, University of London

Lab Members